Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions.
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Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in miceThe Roles of Glutathione Peroxidases during Embryo DevelopmentInactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in miceDopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4.Selenoproteins: molecular pathways and physiological roles.Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors.Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy.The subcellular location of selenoproteins and the impact on their function.AMPK: a master energy regulator for gonadal function.Oxidative stress is involved in age-dependent spermatogenic damage of Immp2l mutant miceAcquired multiple acyl-CoA dehydrogenase deficiency and marked selenium deficiency causing severe rhabdomyolysis in a horse.Mitochondria-targeted antioxidant SkQ1 improves spermatogenesis in Immp2l mutant mice.The cytosolic or the mitochondrial glutathione peroxidase-type tryparedoxin peroxidase is sufficient to protect procyclic Trypanosoma brucei from iron-mediated mitochondrial damage and lysis.The nuclear form of glutathione peroxidase 4 is associated with sperm nuclear matrix and is required for proper paternal chromatin decondensation at fertilization.Mouse Models that Target Individual Selenoproteins
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Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Short form glutathione peroxid ...... matic mitochondrial functions.
@en
Short form glutathione peroxid ...... matic mitochondrial functions.
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type
label
Short form glutathione peroxid ...... matic mitochondrial functions.
@en
Short form glutathione peroxid ...... matic mitochondrial functions.
@nl
prefLabel
Short form glutathione peroxid ...... matic mitochondrial functions.
@en
Short form glutathione peroxid ...... matic mitochondrial functions.
@nl
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P2860
P356
P1476
Short form glutathione peroxid ...... matic mitochondrial functions.
@en
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Arlan Richardson
Christi A Walter
Hanyu Liang
Si-Eun Yoo
P2860
P304
30836-30844
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10.1074/JBC.M109.032839
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P577
2009-09-10T00:00:00Z