MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.
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Mitochondrially localised MUL1 is a novel modulator of antiviral signalingMicrobiota-based treatments in alcoholic liver diseaseLipoproteins of Gram-Positive Bacteria: Key Players in the Immune Response and VirulenceLinking diet to acne metabolomics, inflammation, and comedogenesis: an updateDeconstructing innate immune signaling in myelodysplastic syndromesCrystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protectionCD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell linesUsing 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice.The CO donor CORM-2 inhibits LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts.TLR3-mediated NF-{kappa}B signaling in human esophageal epithelial cells.Ablation of Akt2 protects against lipopolysaccharide-induced cardiac dysfunction: role of Akt ubiquitination E3 ligase TRAF6.Toll-Like Receptors and Cancer: MYD88 Mutation and Inflammation.Macrophage-activating lipopeptide-2 requires Mal and PI3K for efficient induction of heme oxygenase-1.A novel TLR2-triggered signalling crosstalk synergistically intensifies TNF-mediated IL-6 inductionThe proteasome regulates bacterial CpG DNA-induced signaling pathways in murine macrophagesTargeting Toll-like receptor (TLR) signaling by Toll/interleukin-1 receptor (TIR) domain-containing adapter protein/MyD88 adapter-like (TIRAP/Mal)-derived decoy peptides.TRAM is required for TLR2 endosomal signaling to type I IFN inductionTLR4-MyD88/Mal-NF-kB axis is involved in infection of HSV-2 in human cervical epithelial cells.Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways.The human transcriptome during nontyphoid Salmonella and HIV coinfection reveals attenuated NFkappaB-mediated inflammation and persistent cell cycle disruption.Pathophysiology of the antiphospholipid antibody syndrome.TREM-1 amplifies corneal inflammation after Pseudomonas aeruginosa infection by modulating Toll-like receptor signaling and Th1/Th2-type immune responses.TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia.Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylationPoxviral protein A46 antagonizes Toll-like receptor 4 signaling by targeting BB loop motifs in Toll-IL-1 receptor adaptor proteins to disrupt receptor:adaptor interactionsNatural small molecule FMHM inhibits lipopolysaccharide-induced inflammatory response by promoting TRAF6 degradation via K48-linked polyubiquitinationERK5 protein promotes, whereas MEK1 protein differentially regulates, the Toll-like receptor 2 protein-dependent activation of human endothelial cells and monocytes.The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.Association between the TLR2 Arg753Gln polymorphism and the risk of sepsis: a meta-analysis.Epithelial cells augment barrier function via activation of the Toll-like receptor 2/phosphatidylinositol 3-kinase pathway upon recognition of Salmonella enterica serovar Typhimurium curli fibrils in the gut.A novel function of MUC18: amplification of lung inflammation during bacterial infection.Meta-analysis on the associations of TLR2 gene polymorphisms with pulmonary tuberculosis susceptibility among Asian populations.Alcoholic liver disease and the gut-liver axis.The unfolding web of innate immune dysregulation in alcoholic liver injury.Pattern recognition receptors: sentinels in innate immunity and targets of new vaccine adjuvants.The role of gut-liver axis in the pathogenesis of liver cirrhosis and portal hypertension.Mal, more than a bridge to MyD88.Toll-Like Receptors and Tissue Remodeling: The Pro/Cons Recent Findings.A Systems Biology Approach to Understanding Alcoholic Liver Disease Molecular Mechanism: The Development of Static and Dynamic Models.Tumor Necrosis Factor Receptor-Associated Factor 6 (TRAF6) Mediates Ubiquitination-Dependent STAT3 Activation upon Salmonella enterica Serovar Typhimurium Infection.
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P2860
MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
MyD88 adapter-like (Mal)/TIRAP ...... paB proinflammatory responses.
@en
type
label
MyD88 adapter-like (Mal)/TIRAP ...... paB proinflammatory responses.
@en
prefLabel
MyD88 adapter-like (Mal)/TIRAP ...... paB proinflammatory responses.
@en
P2093
P2860
P356
P1476
MyD88 adapter-like (Mal)/TIRAP ...... ppaB proinflammatory responses
@en
P2093
Brett Verstak
Douglas T Golenbock
Kamalpreet Nagpal
Stephen P Bottomley
P2860
P304
24192-24203
P356
10.1074/JBC.M109.023044
P407
P577
2009-07-10T00:00:00Z