Synthesis, solution structure, and phylum selectivity of a spider delta-toxin that slows inactivation of specific voltage-gated sodium channel subtypes.
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Altered cardiac electrophysiology and SUDEP in a model of Dravet syndromePhyla- and Subtype-Selectivity of CgNa, a Na Channel Toxin from the Venom of the Giant Caribbean Sea Anemone Condylactis GiganteaUnique bell-shaped voltage-dependent modulation of Na+ channel gating by novel insect-selective toxins from the spider Agelena orientalisThe insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channelsThe insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loopUse of venom peptides to probe ion channel structure and function.A comparison between the recombinant expression and chemical synthesis of a short cysteine-rich insecticidal spider peptide.Comparative analysis of tissue-specific transcriptomes in the funnel-web spider Macrothele calpeiana (Araneae, Hexathelidae).Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana.Molecular cloning and in silico characterization of knottin peptide, U2-SCRTX-Lit2, from brown spider (Loxosceles intermedia) venom glands.Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation.Discovery of a Novel Na1.7 Inhibitor From Venom With Potent Analgesic Efficacy
P2860
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P2860
Synthesis, solution structure, and phylum selectivity of a spider delta-toxin that slows inactivation of specific voltage-gated sodium channel subtypes.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Synthesis, solution structure, ...... gated sodium channel subtypes.
@en
Synthesis, solution structure, ...... gated sodium channel subtypes.
@nl
type
label
Synthesis, solution structure, ...... gated sodium channel subtypes.
@en
Synthesis, solution structure, ...... gated sodium channel subtypes.
@nl
prefLabel
Synthesis, solution structure, ...... gated sodium channel subtypes.
@en
Synthesis, solution structure, ...... gated sodium channel subtypes.
@nl
P2093
P2860
P356
P1476
Synthesis, solution structure, ...... gated sodium channel subtypes.
@en
P2093
Bert Billen
Elba Villegas
Gerardo Corzo
Graham M Nicholson
Hideki Nishio
Jan Tytgat
Michelle J Little
Nahoko Yamaji
Yuji Nishiuchi
P2860
P304
24568-24582
P356
10.1074/JBC.M109.030841
P407
P577
2009-07-10T00:00:00Z