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Population genomics of parallel adaptation in threespine stickleback using sequenced RAD tagsCrohn's disease risk alleles on the NOD2 locus have been maintained by natural selection on standing variationWeak selection and protein evolutionMolecular Signatures of Natural Selection for Polymorphic Genes of the Human Dopaminergic and Serotonergic Systems: A ReviewTrans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune responseFifteen years of genomewide scans for selection: trends, lessons and unaddressed genetic sources of complicationGenetics of autoimmune diseases: insights from population geneticsRecent human adaptation: genomic approaches, interpretation and insightsPopulation genetic tools for dissecting innate immunity in humansExpression of the Blood-Group-Related Gene B4galnt2 Alters Susceptibility to Salmonella InfectionUnderstanding rare and common diseases in the context of human evolutionCan the experimental evolution programme help us elucidate the genetic basis of adaptation in nature?Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosalMorphological and population genomic evidence that human faces have evolved to signal individual identityThe emergence of human-evolutionary medical genomicsA model-based approach for identifying signatures of ancient balancing selection in genetic dataHyperdiverse gene cluster in snail host conveys resistance to human schistosome parasitesLong-term balancing selection at the blood group-related gene B4galnt2 in the genus Mus (Rodentia; Muridae).Natural Selection in the Great ApesHeritability and genomics of gene expression in peripheral blood.Identifying the genes underlying quantitative traits: a rationale for the QTN programmeEpidemiological mechanisms of genetic resistance to kuru.Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.Influence of immune responses in gene/stem cell therapies for muscular dystrophies.Molecular hyperdiversity and evolution in very large populations.Genetics of focal segmental glomerulosclerosis and human immunodeficiency virus-associated collapsing glomerulopathy: the role of MYH9 genetic variation.The characterisation of three types of genes that overlie copy number variable regionsA small system--high-resolution study of metabolic adaptation in the central metabolic pathway to temperate climates in Drosophila melanogasterBalancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolvingGenetic adaptation of the antibacterial human innate immunity networkMolecular spandrels: tests of adaptation at the genetic level.Allele frequency-based and polymorphism-versus-divergence indices of balancing selection in a new filtered set of polymorphic genes in Plasmodium falciparum.Evolutionary forces shaping genomic islands of population differentiation in humansPersonal receptor repertoires: olfaction as a model.Continental-scale footprint of balancing and positive selection in a small rodent (Microtus arvalis).Impact of constitutional copy number variants on biological pathway evolutionPhred-Phrap package to analyses tools: a pipeline to facilitate population genetics re-sequencing studies.Balancing selection on a regulatory region exhibiting ancient variation that predates human-neandertal divergenceA hierarchical Bayesian model for next-generation population genomics.Cross-amplification and validation of SNPs conserved over 44 million years between seals and dogs
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targets of balancing selection in the human genome.
@en
Targets of balancing selection in the human genome.
@nl
type
label
Targets of balancing selection in the human genome.
@en
Targets of balancing selection in the human genome.
@nl
prefLabel
Targets of balancing selection in the human genome.
@en
Targets of balancing selection in the human genome.
@nl
P2093
P2860
P50
P356
P1476
Targets of balancing selection in the human genome.
@en
P2093
Adam R Boyko
Amit Indap
Andrew G Clark
Dara G Torgerson
Jeremiah D Degenhardt
Melissa J Hubisz
Ryan N Gutenkunst
Thomas J White
P2860
P304
P356
10.1093/MOLBEV/MSP190
P577
2009-08-27T00:00:00Z