A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
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Drosophila as a Potential Model for Ocular TumorsNon-autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesisOf flies, mice, and men: evolutionarily conserved tissue damage responses and agingMultiple polymer architectures of human polyhomeotic homolog 3 sterile alpha motifSomatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.The legacy of Drosophila imaginal discsJAK/STAT pathway dysregulation in tumors: a Drosophila perspectiveLoss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemiaMultiple strategies of oxygen supply in Drosophila malignancies identify tracheogenesis as a novel cancer hallmarkMutations in the polycomb group gene polyhomeotic lead to epithelial instability in both the ovary and wing imaginal disc in Drosophila.Polycomb group genes Psc and Su(z)2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signalingDiverse patterns of genomic targeting by transcriptional regulators in Drosophila melanogaster.Gene networks and the neuroendocrine regulation of pubertyTNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration.Organogenesis and tumorigenesis: insight from the JAK/STAT pathway in the Drosophila eyeThe transcriptional control of female puberty.Functional genomics in Drosophila models of human disease.Polycomb group genes Psc and Su(z)2 maintain somatic stem cell identity and activity in Drosophila.Polycomb preferentially targets stalled promoters of coding and noncoding transcriptsPolycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes.Brain regeneration in Drosophila involves comparison of neuronal fitness.Polycomb silencing of the Drosophila 4E-BP gene regulates imaginal disc cell growth.During Drosophila disc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay.Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes.Preventing Age-Related Decline of Gut Compartmentalization Limits Microbiota Dysbiosis and Extends LifespandBRWD3 Regulates Tissue Overgrowth and Ectopic Gene Expression Caused by Polycomb Group Mutations.Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila.Where gene discovery turns into systems biology: genome-scale RNAi screens in DrosophilaSex, stem cells and tumors in the Drosophila ovaryMapping polycomb response elements at the Drosophilla melanogaster giant locus.Three-Dimensional Genome Organization and Function in Drosophila.A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primatesInterface Contractility between Differently Fated Cells Drives Cell Elimination and Cyst Formation.Dissecting social cell biology and tumors using Drosophila genetics.Signaling epigenetics: novel insights on cell signaling and epigenetic regulation.Extra sex combs, chromatin, and cancer: exploring epigenetic regulation and tumorigenesis in Drosophila.Drosophila cancer models.Regulation of proliferation, cell competition, and cellular growth by the Drosophila JAK-STAT pathway.Sensing cellular states--signaling to chromatin pathways targeting Polycomb and Trithorax group function.Wisdom from the fly.
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A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
@en
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
@nl
type
label
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
@en
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
@nl
prefLabel
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
@en
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
@nl
P2860
P50
P356
P1433
P1476
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
@en
P2093
Brandon D Bunker
David Bilder
P2860
P2888
P304
P356
10.1038/NG.445
P407
P577
2009-09-13T00:00:00Z
P5875
P6179
1052599388