Chronic, topical exposure to benzo[a]pyrene induces relatively high steady-state levels of DNA adducts in target tissues and alters kinetics of adduct loss.
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The tumor promoter TPA enhances benzo[a]pyrene and benzo[a]pyrene diolepoxide mutagenesis in Big Blue mouse skin.Impact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons.Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations.Carcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F-344 rats.Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants.Whole DNA methylome profiling in mice exposed to secondhand smokeThe role of polycyclic aromatic hydrocarbon-DNA adducts in inducing mutations in mouse skinQuantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with (R)- or (S)-N'-nitrosonornicotine (NNN) in a carcinogenicity study.Review on proteomic analyses of benzo[a]pyrene toxicity.Early age at smoking initiation and tobacco carcinogen DNA damage in the lung.A proposed methodology of cancer risk assessment modeling using biomarkers.Genotoxicity of organic extracts of house dust from Shanxi, China.Potential application of benzo(a)pyrene-associated adducts (globin or lipid) as blood biomarkers for target organ exposure and human risk assessment.The long persistence of pyrrolizidine alkaloid-derived DNA adducts in vivo: kinetic study following single and multiple exposures in male ICR mice.
P2860
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P2860
Chronic, topical exposure to benzo[a]pyrene induces relatively high steady-state levels of DNA adducts in target tissues and alters kinetics of adduct loss.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Chronic, topical exposure to b ...... lters kinetics of adduct loss.
@en
Chronic, topical exposure to b ...... lters kinetics of adduct loss.
@nl
type
label
Chronic, topical exposure to b ...... lters kinetics of adduct loss.
@en
Chronic, topical exposure to b ...... lters kinetics of adduct loss.
@nl
prefLabel
Chronic, topical exposure to b ...... lters kinetics of adduct loss.
@en
Chronic, topical exposure to b ...... lters kinetics of adduct loss.
@nl
P2093
P2860
P356
P1476
Chronic, topical exposure to b ...... lters kinetics of adduct loss.
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.15.7789
P407
P577
1996-07-01T00:00:00Z