Ceramide biosynthesis in keratinocyte and its role in skin function.
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Mutations in CERS3 cause autosomal recessive congenital ichthyosis in humansELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesisCeramide synthases at the centre of sphingolipid metabolism and biologyLong-chain bases of sphingolipids are transported into cells via the acyl-CoA synthetasesEffects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids.Identification of the phytosphingosine metabolic pathway leading to odd-numbered fatty acids.The role of epidermal sphingolipids in dermatologic diseasesThe human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the 'fused genes' familyPotential Applications of Phyto-Derived Ceramides in Improving Epidermal Barrier Function.Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism.Analyzing and mapping sweat metabolomics by high-resolution NMR spectroscopy.Metabolism of very long-chain Fatty acids: genes and pathophysiology.Essential role of the cytochrome P450 CYP4F22 in the production of acylceramide, the key lipid for skin permeability barrier formation.Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores.Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation.Epidermal expression of an Elovl4 transgene rescues neonatal lethality of homozygous Stargardt disease-3 mice.The role of fatty acid elongation in epidermal structure and function.Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.Triangulated mal-signaling in Alzheimer's disease: roles of neurotoxic ceramides, ER stress, and insulin resistance reviewedTreatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide.Producing human ceramide-NS by metabolic engineering using yeast Saccharomyces cerevisiae.Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.Disruption of the Sjögren-Larsson Syndrome Gene Aldh3a2 in Mice Increases Keratinocyte Growth and Retards Skin Barrier RecoveryImpaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid productionContribution of the Hair Follicular Pathway to Total Skin Permeation of Topically Applied and Exposed Chemicals.Very long chain sphingolipids: tissue expression, function and synthesis.Current evidence of skin barrier dysfunction in human and canine atopic dermatitis.Bioactives from probiotics for dermal health: functions and benefits.The stratum corneum: the rampart of the mammalian body.Stratum corneum fatty acids: their critical role in preserving barrier integrity during cleansing.Epidermal barriersThe chemistry and biology of 6-hydroxyceramide, the youngest member of the human sphingolipid family.Role of Sphingolipids and Metabolizing Enzymes in Hematological Malignancies.The Herbal Bitter Drug Gentiana lutea Modulates Lipid Synthesis in Human Keratinocytes In Vitro and In Vivo.Fam20C is under the control of sphingolipid signaling in human cell lines.Hyaluronan tetrasaccharides stimulate ceramide production through upregulated mRNA expression of ceramide synthesis-associated enzymes.Dry skin in the winter is related to the ceramide profile in the stratum corneum and can be improved by treatment with a Eucalyptus extract.Analysis of ceramide metabolites in differentiating epidermal keratinocytes treated with calcium or vitamin C.Human as the Ultimate Wound Healing Model: Strategies for Studies Investigating the Dermal Lipidome.Therapeutic implications of bioactive sphingolipids: A focus on colorectal cancer.
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Ceramide biosynthesis in keratinocyte and its role in skin function.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Ceramide biosynthesis in keratinocyte and its role in skin function.
@en
Ceramide biosynthesis in keratinocyte and its role in skin function.
@nl
type
label
Ceramide biosynthesis in keratinocyte and its role in skin function.
@en
Ceramide biosynthesis in keratinocyte and its role in skin function.
@nl
prefLabel
Ceramide biosynthesis in keratinocyte and its role in skin function.
@en
Ceramide biosynthesis in keratinocyte and its role in skin function.
@nl
P2093
P1433
P1476
Ceramide biosynthesis in keratinocyte and its role in skin function.
@en
P2093
Akio Kihara
Kiyomi Tsuji
Susumu Mitsutake
Yasuyuki Igarashi
Yukiko Mizutani
P304
P356
10.1016/J.BIOCHI.2009.04.001
P577
2009-04-11T00:00:00Z