Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues. - Wikidata - awgldk - TriplyDB

Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues.

Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues.

http://www.wikidata.org/entity/Q37445042

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Epigenetics and aging Restricting retrotransposons: a review The dark side of circulating nucleic acids Molecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Preferential retrotransposition in aging yeast mother cells is correlated with increased genome instability.Reorganization of chromosome architecture in replicative cellular senescence The aging clock and circadian control of metabolism and genome stability Growth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocations Redox theory of aging Human Genomics. Sleeping dogs of the genome Regulatory activities of transposable elements: from conflicts to benefits.SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.Extension of Saccharomyces paradoxus chronological lifespan by retrotransposons in certain media conditions is associated with changes in reactive oxygen species.Effects of heat and UV radiation on the mobilization of transposon mariner-Mos1.Interventions to Slow Aging in Humans: Are We Ready?Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS Somatizing the transposons action.A conserved role for the ESCRT membrane budding complex in LINE retrotransposition Epigenetic regulation of ageing: linking environmental inputs to genomic stability.TEtranscripts: a package for including transposable elements in differential expression analysis of RNA-seq datasets.Antagonistic roles of Nibbler and Hen1 in modulating piRNA 3' ends in Drosophila How retrotransposons shape genome regulation.Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila.Tightening the connection between transposable element mobilization and aging.What might retrotransposons teach us about aging?Effect of aging on stem cells.Aging and Lung Disease. Clinical Impact and Cellular and Molecular Pathways.Nucleolar aggresomes mediate release of pericentric heterochromatin and nuclear destruction of genotoxically treated cancer cells.SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence.Epigenetic Mechanisms of Longevity and Aging.The Chromatin Landscape of Cellular Senescence.SIRT6: Novel Mechanisms and Links to Aging and Disease.Genome instability: a conserved mechanism of ageing?Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence.Aging in Rats Differentially Affects Markers of Transcriptional and Translational Capacity in Soleus and Plantaris Muscle.A Genome-Wide Chronological Study of Gene Expression and Two Histone Modifications, H3K4me3 and H3K9ac, during Developmental Leaf Senescence.Meeting Report: The Role of the Mobilome in Cancer.The Piwi-piRNA pathway: road to immortality.Piwi Is Required to Limit Exhaustion of Aging Somatic Stem Cells.

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Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues.

http://www.wikidata.org/entity/Q37445042

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article científic

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bilimsel makale

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scientific article published on December 2013

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vedecký článok

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vetenskaplig artikel

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Transposable elements become a ...... ing mammalian somatic tissues.

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Transposable elements become a ...... ing mammalian somatic tissues.

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Transposable elements become a ...... ing mammalian somatic tissues.

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Transposable elements become a ...... ing mammalian somatic tissues.

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Transposable elements become a ...... ing mammalian somatic tissues.

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Transposable elements become a ...... ing mammalian somatic tissues.

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Abigail L Peterson

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John M Sedivy

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Marco De Cecco

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Nicola Neretti

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Steven W Criscione

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867-883

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10.18632/AGING.100621

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