Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues.
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Epigenetics and agingRestricting retrotransposons: a reviewThe dark side of circulating nucleic acidsMolecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Preferential retrotransposition in aging yeast mother cells is correlated with increased genome instability.Reorganization of chromosome architecture in replicative cellular senescenceThe aging clock and circadian control of metabolism and genome stabilityGrowth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocationsRedox theory of agingHuman Genomics. Sleeping dogs of the genomeRegulatory activities of transposable elements: from conflicts to benefits.SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.Extension of Saccharomyces paradoxus chronological lifespan by retrotransposons in certain media conditions is associated with changes in reactive oxygen species.Effects of heat and UV radiation on the mobilization of transposon mariner-Mos1.Interventions to Slow Aging in Humans: Are We Ready?Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALSSomatizing the transposons action.A conserved role for the ESCRT membrane budding complex in LINE retrotranspositionEpigenetic regulation of ageing: linking environmental inputs to genomic stability.TEtranscripts: a package for including transposable elements in differential expression analysis of RNA-seq datasets.Antagonistic roles of Nibbler and Hen1 in modulating piRNA 3' ends in DrosophilaHow retrotransposons shape genome regulation.Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila.Tightening the connection between transposable element mobilization and aging.What might retrotransposons teach us about aging?Effect of aging on stem cells.Aging and Lung Disease. Clinical Impact and Cellular and Molecular Pathways.Nucleolar aggresomes mediate release of pericentric heterochromatin and nuclear destruction of genotoxically treated cancer cells.SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence.Epigenetic Mechanisms of Longevity and Aging.The Chromatin Landscape of Cellular Senescence.SIRT6: Novel Mechanisms and Links to Aging and Disease.Genome instability: a conserved mechanism of ageing?Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence.Aging in Rats Differentially Affects Markers of Transcriptional and Translational Capacity in Soleus and Plantaris Muscle.A Genome-Wide Chronological Study of Gene Expression and Two Histone Modifications, H3K4me3 and H3K9ac, during Developmental Leaf Senescence.Meeting Report: The Role of the Mobilome in Cancer.The Piwi-piRNA pathway: road to immortality.Piwi Is Required to Limit Exhaustion of Aging Somatic Stem Cells.
P2860
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P2860
Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transposable elements become a ...... ing mammalian somatic tissues.
@en
Transposable elements become a ...... ing mammalian somatic tissues.
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type
label
Transposable elements become a ...... ing mammalian somatic tissues.
@en
Transposable elements become a ...... ing mammalian somatic tissues.
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prefLabel
Transposable elements become a ...... ing mammalian somatic tissues.
@en
Transposable elements become a ...... ing mammalian somatic tissues.
@nl
P2093
P2860
P356
P1433
P1476
Transposable elements become a ...... ing mammalian somatic tissues.
@en
P2093
Abigail L Peterson
John M Sedivy
Marco De Cecco
Nicola Neretti
Steven W Criscione
P2860
P304
P356
10.18632/AGING.100621
P577
2013-12-01T00:00:00Z