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T-regulatory cell modulation: the future of cancer immunotherapy?

T-regulatory cell modulation: the future of cancer immunotherapy?

http://www.wikidata.org/entity/Q37454346

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Suppression, subversion and escape: the role of regulatory T cells in cancer progression The interplay of immunotherapy and chemotherapy: harnessing potential synergies Vaccines versus immunotherapy: overview of approaches in deciding between options Immunotherapy of malignant disease with tumor antigen-specific monoclonal antibodies.Chemoimmunotherapy.Infection, immunoregulation, and cancer.Translating tumor antigens into cancer vaccines Co-administration of GP96 and Her2/neu DNA vaccine in a Her2 breast cancer model Adjuvant activity of GP96 C-terminal domain towards Her2/neu DNA vaccine is fusion direction-dependent.Safety, pharmacokinetics, and immunomodulatory effects of lenalidomide in children and adolescents with relapsed/refractory solid tumors or myelodysplastic syndrome: a Children's Oncology Group Phase I Consortium report.Immunological and clinical effects of vaccines targeting p53-overexpressing malignancies.Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers.Radiotherapy suppressed tumor-specific recruitment of regulator T cells via up-regulating microR-545 in Lewis lung carcinoma cells Regulatory T-cells in chronic lymphocytic leukemia and autoimmune diseases Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.Immunotherapy: shifting the balance of cell-mediated immunity and suppression in human prostate cancer.Use of anti-cancer drugs, mitocans, to enhance the immune responses against tumors.Unravelling the complexity of cancer-immune system interplay.Current status and future applications of cellular therapies for cancer.Myeloid-derived suppressor cells--their role in haemato-oncological malignancies and other cancers and possible implications for therapy.Low-dose radiation therapy of cancer: role of immune enhancement.Exploitation of the propulsive force of chemotherapy for improving the response to cancer immunotherapy.Tumor microenvironment: a main actor in the metastasis process.Targeting the MHC Class II antigen presentation pathway in cancer immunotherapy.Synthetic adjuvants for vaccine formulations: phytol derivatives.Chemoimmunotherapy: reengineering tumor immunity.Exploiting dendritic cells in the development of cancer vaccines.Regulatory T-cell cytokines in patients with nonsegmental vitiligo.Challenges in vaccine therapy in hematological malignancies and strategies to overcome them.Low-dose radiation may be a novel approach to enhance the effectiveness of cancer therapeutics.Human leukocyte antigen-G is closely associated with tumor immune escape in gastric cancer by increasing local regulatory T cells.Depletion of CD25⁺ T cells from hematopoietic stem cell grafts increases posttransplantation vaccine-induced immunity to neuroblastoma.The expression levels of transcription factors T-bet, GATA-3, RORγt and FOXP3 in peripheral blood lymphocyte (PBL) of patients with liver cancer and their significance.Effects of feeding untreated, pasteurized and acidified waste milk and bunk tank milk on the performance, serum metabolic profiles, immunity, and intestinal development in Holstein calves.Invasive front of colorectal cancer: dynamic interface of pro-/anti-tumor factors.Regulatory T-cells in chronic lymphocytic leukemia: actor or innocent bystander?Ribavirin modulates the conversion of human CD4(+) CD25(-) T cell to CD4(+) CD25(+) FOXP3(+) T cell via suppressing interleukin-10-producing regulatory T cell.Immunotherapy for Breast Cancer: Current and Future Strategies.A study for proposal of use of regulatory T cells as a prognostic marker and establishing an optimal threshold level for their expression in chronic lymphocytic leukemia.ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells.

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T-regulatory cell modulation: the future of cancer immunotherapy?

http://www.wikidata.org/entity/Q37454346

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 21 April 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

T-regulatory cell modulation: the future of cancer immunotherapy?

@en

T-regulatory cell modulation: the future of cancer immunotherapy?

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type

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T-regulatory cell modulation: the future of cancer immunotherapy?

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T-regulatory cell modulation: the future of cancer immunotherapy?

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prefLabel

T-regulatory cell modulation: the future of cancer immunotherapy?

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T-regulatory cell modulation: the future of cancer immunotherapy?

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British Journal of Cancer

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T-regulatory cell modulation: the future of cancer immunotherapy?

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A Dalgleish

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B Meyer

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C Galustian

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D Kumar

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J Copier

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M Bodman-Smith

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S Nizar

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P2860

Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Cloning and characterization of GITR ligand

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

Inability to mediate prolonged reduction of regulatory T Cells after transfer of autologous CD25-depleted PBMC and interleukin-2 after lymphodepleting chemotherapy

Administration of a CD25-directed immunotoxin, LMB-2, to patients with metastatic melanoma induces a selective partial reduction in regulatory T cells in vivo.

Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer.

The heterogeneity of the kinetics of response to ipilimumab in metastatic melanoma: patient cases.

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

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1697-1703

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scholarly article

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10.1038/SJ.BJC.6605040

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11

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100

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2009-04-21T00:00:00Z

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24346441

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19384299

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T-lymphocyte subsets

lymphocyte subsets

hemic and immune systems

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