Interaction of torsinA with its major binding partners is impaired by the dystonia-associated DeltaGAG deletion.
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Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinAArresting a Torsin ATPase reshapes the endoplasmic reticulumRegulation of Torsin ATPases by LAP1 and LULL1Lamina-associated polypeptide 1: protein interactions and tissue-selective functionsTorsins: not your typical AAA+ ATPasesThe nuclear envelope at a glanceA molecular mechanism underlying the neural-specific defect in torsinA mutant miceTorsinA hypofunction causes abnormal twisting movements and sensorimotor circuit neurodegenerationThe BiP molecular chaperone plays multiple roles during the biogenesis of torsinA, an AAA+ ATPase associated with the neurological disease early-onset torsion dystonia.Torsin ATPases: Harnessing Dynamic Instability for Function.The nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component.Current Gaps in the Understanding of the Subcellular Distribution of Exogenous and Endogenous Protein TorsinA.A unique redox-sensing sensor II motif in TorsinA plays a critical role in nucleotide and partner binding.The zebrafish homologue of the human DYT1 dystonia gene is widely expressed in CNS neurons but non-essential for early motor system developmentThe mechanism of Torsin ATPase activation.Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunctionGenetic and clinical features of primary torsion dystonia.The nuclear envelope protein, LAP1B, is a novel protein phosphatase 1 substrate.Intracellular complexes of the early-onset torsion dystonia-associated AAA+ ATPase TorsinA.Stable isotope labeling with amino acids in cell culture based mass spectrometry approach to detect transient protein interactions using substrate trapping.How lamina-associated polypeptide 1 (LAP1) activates Torsin.Static retention of the lumenal monotopic membrane protein torsinA in the endoplasmic reticulum.Inherited isolated dystonia: clinical genetics and gene function.The pathogenic human Torsin A in Drosophila activates the unfolded protein response and increases susceptibility to oxidative stress.An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 ΔGAG knock-in mice.Access of torsinA to the inner nuclear membrane is activity dependent and regulated in the endoplasmic reticulum.TorsinA participates in endoplasmic reticulum-associated degradationStructures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.Neuronal Nuclear Membrane Budding Occurs during a Developmental Window Modulated by Torsin Paralogs.Molecular pathways in dystonia.Milestones in dystonia.Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE.Torsin ATPases: structural insights and functional perspectives.TorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movement.Nuclear envelope breakdown induced by herpes simplex virus type 1 involves the activity of viral fusion proteins.Diseases of the Nucleoskeleton.Membrane defects and genetic redundancy: Are we at a turning point for DYT1 dystonia?Update on the Genetics of Dystonia.Lamina Associated Polypeptide 1 (LAP1) Interactome and Its Functional Features.LINCing defective nuclear-cytoskeletal coupling and DYT1 dystonia.
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Interaction of torsinA with its major binding partners is impaired by the dystonia-associated DeltaGAG deletion.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Interaction of torsinA with it ...... -associated DeltaGAG deletion.
@en
Interaction of torsinA with it ...... -associated DeltaGAG deletion.
@nl
type
label
Interaction of torsinA with it ...... -associated DeltaGAG deletion.
@en
Interaction of torsinA with it ...... -associated DeltaGAG deletion.
@nl
prefLabel
Interaction of torsinA with it ...... -associated DeltaGAG deletion.
@en
Interaction of torsinA with it ...... -associated DeltaGAG deletion.
@nl
P2093
P2860
P356
P1476
Interaction of torsinA with it ...... -associated DeltaGAG deletion.
@en
P2093
Phyllis I Hanson
Seema Dalal
Teresa V Naismith
P2860
P304
27866-27874
P356
10.1074/JBC.M109.020164
P407
P577
2009-08-03T00:00:00Z