Mechanism of protection by metallothionein against acetaminophen hepatotoxicity. - Wikidata - awgldk - TriplyDB

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

http://www.wikidata.org/entity/Q37463698

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Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes Current issues with acetaminophen hepatotoxicity--a clinically relevant model to test the efficacy of natural products.Polyinosinic-polycytidylic acid suppresses acetaminophen-induced hepatotoxicity independent of type I interferons and toll-like receptor 3 Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration.Acute ethanol causes hepatic mitochondrial depolarization in mice: role of ethanol metabolism.Hepatitis C virus structural proteins can exacerbate or ameliorate acetaminophen-induced liver injury in mice.Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.Chlorogenic acid prevents acetaminophen-induced liver injury: the involvement of CYP450 metabolic enzymes and some antioxidant signals Acetaminophen: Dose-Dependent Drug Hepatotoxicity and Acute Liver Failure in Patients.An indole derivative protects against acetaminophen-induced liver injury by directly binding to N-acetyl-p-benzoquinone imine in mice.Fas receptor-deficient lpr mice are protected against acetaminophen hepatotoxicity due to higher glutathione synthesis and enhanced detoxification of oxidant stress.Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning Protective effect of metallothionein on oxidative stress-induced DNA damage.Pharmacokinetic variations in cancer patients with liver dysfunction: applications and challenges of pharmacometabolomics.Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity.Kampo formula "Hochu-ekki-to" suppressed carbon tetrachloride-induced hepatotoxicity in mice.In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI.

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Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

http://www.wikidata.org/entity/Q37463698

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 14 October 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

@en

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

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type

label

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

@en

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

@nl

prefLabel

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

@en

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

@nl

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J.TAAP.2009.10.006

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Toxicology and Applied Pharmacology

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Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

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Antonio Artigues

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Anwar Farhood

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Chieko Saito

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Hartmut Jaeschke

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Hui-Min Yan

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Maria T Villar

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Regulation of glutathione synthesis

Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: correlation of nuclear Ca2+ accumulation and early DNA fragmentation with cell death

Selective protein arylation and acetaminophen-induced hepatotoxicity.

Identification of the hepatic protein targets of reactive metabolites of acetaminophen in vivo in mice using two-dimensional gel electrophoresis and mass spectrometry.

Metallothionein: an intracellular protein to protect against cadmium toxicity.

Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine.

Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study.

Free radical scavenging actions of metallothionein isoforms I and II.

Zinc supplementation prevents alcoholic liver injury in mice through attenuation of oxidative stress.

The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity.

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182-190

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scholarly article

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10.1016/J.TAAP.2009.10.006

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