The divalent metal transporter homologues SMF-1/2 mediate dopamine neuron sensitivity in caenorhabditis elegans models of manganism and parkinson disease.
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Using C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseasesNeuronal responses to stress and injury in C. elegansManganese-induced Neurotoxicity: From C. elegans to HumansExtracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegansA zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity.Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms.The role of iron uptake in pathogenicity and symbiosis in Photorhabdus luminescens TT01.Caenorhabditis elegans: a model to investigate oxidative stress and metal dyshomeostasis in Parkinson's diseaseMechanisms of iron metabolism in Caenorhabditis elegansBehavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models.HIF-1 regulates iron homeostasis in Caenorhabditis elegans by activation and inhibition of genes involved in iron uptake and storageSKN-1/Nrf2 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of methylmercury toxicity.Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery.The Energy Metabolism in Caenorhabditis elegans under The Extremely Low-Frequency Electromagnetic Field ExposureUltrastructural Changes of Caudate Nucleus in Mice Chronically Treated with Manganese.Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans.Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans by preventing oxidative stress.Copper Oxide Nanoparticles Impact Several Toxicological Endpoints and Cause Neurodegeneration in Caenorhabditis elegans.The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models.Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutationsMetal-induced neurodegeneration in C. elegans.The metal transporter SMF-3/DMT-1 mediates aluminum-induced dopamine neuron degeneration.The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganismThe putative multidrug resistance protein MRP-7 inhibits methylmercury-associated animal toxicity and dopaminergic neurodegeneration in Caenorhabditis elegansThe Caenorhabiditis elegans model as a reliable tool in neurotoxicology.Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases.Manganese accumulation in the CNS and associated pathologies.New animal models of Parkinson's disease.Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.Modeling human neurodegenerative diseases in transgenic systems.Chronic exposure to graphene-based nanomaterials induces behavioral deficits and neural damage in Caenorhabditis elegans.RNA-Seq Reveals Acute Manganese Exposure Increases Endoplasmic Reticulum Related and Lipocalin mRNAs in Caenorhabditis elegans.Iron promotes protein insolubility and aging in C. elegans.Manganese disturbs metal and protein homeostasis in Caenorhabditis elegans.Caenorhabditis elegans neuron degeneration and mitochondrial suppression caused by selected environmental chemicalsNeurodegeneration Induced by Metals in Caenorhabditis elegans.PBPK/PD assessment for Parkinson's disease risk posed by airborne pesticide paraquat exposure.Ceruloplasmin is Involved in the Nigral Iron Accumulation of 6-OHDA-Lesioned Rats.Modeling Parkinson's Disease in C. elegans.C. elegans as a model in developmental neurotoxicology.
P2860
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P2860
The divalent metal transporter homologues SMF-1/2 mediate dopamine neuron sensitivity in caenorhabditis elegans models of manganism and parkinson disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The divalent metal transporter ...... nganism and parkinson disease.
@en
The divalent metal transporter ...... nganism and parkinson disease.
@nl
type
label
The divalent metal transporter ...... nganism and parkinson disease.
@en
The divalent metal transporter ...... nganism and parkinson disease.
@nl
prefLabel
The divalent metal transporter ...... nganism and parkinson disease.
@en
The divalent metal transporter ...... nganism and parkinson disease.
@nl
P2093
P2860
P921
P356
P1476
The divalent metal transporter ...... nganism and parkinson disease.
@en
P2093
Jennifer Levora
Raja Settivari
Richard Nass
P2860
P304
35758-35768
P356
10.1074/JBC.M109.051409
P407
P577
2009-12-01T00:00:00Z