TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.
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EVER2 protein binds TRADD to promote TNF-α-induced apoptosiscIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)Poly-ubiquitination in TNFR1-mediated necroptosisAPI2-MALT1 oncoprotein promotes lymphomagenesis via unique program of substrate ubiquitination and proteolysisThe two faces of receptor interacting protein kinase-1Ubiquitin in the immune systemViral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathwaysGetting TRAIL back on track for cancer therapyCrystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and RegulationThe seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosisRegulation of tumour necrosis factor signalling: live or let dieRIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibitionRIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKLCellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitmentBacterial DNA Protects Monocytic Cells against HIV-Vpr-Induced Mitochondrial Membrane Depolarization.Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor.Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.Screening for the protective effect target of deproteinized extract of calf blood and its mechanisms in mice with CCl4-induced acute liver injury.The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay.Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling.A p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-alpha.TNF receptor-1 (TNF-R1) ubiquitous scaffolding and signaling protein interacts with TNF-R1 and TRAF2 via an N-terminal docking interface.Emerging complexity of protein ubiquitination in the NF-κB pathway.The API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-κB signaling.A novel TNF receptor-associated factor 6 binding domain mediates NF-kappa B signaling by the common cytokine receptor beta subunit.An integrated approach to uncover driver genes in breast cancer methylation genomes.In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFα and ROS production.Inhibitor of apoptosis proteins as intracellular signaling intermediates.FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma.The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell carcinoma of the skinSHARPIN is a key regulator of immune and inflammatory responsesIκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformationTNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in miceMolecular basis of NF-κB signalingTRAF molecules in cell signaling and in human diseasesTNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification.Caspase-8: not so silently deadly.
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TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
TRAF2 must bind to cellular in ...... prevent tnf-induced apoptosis.
@en
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor
@nl
type
label
TRAF2 must bind to cellular in ...... prevent tnf-induced apoptosis.
@en
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor
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prefLabel
TRAF2 must bind to cellular in ...... prevent tnf-induced apoptosis.
@en
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor
@nl
P2093
P2860
P50
P356
P1476
TRAF2 must bind to cellular in ...... prevent tnf-induced apoptosis
@en
P2093
Angelina J Davidson
Anna C Schmukle
Bernard A Callus
Delara Pantaki
Henning Walczak
Holly Carter
James E Vince
Rebecca Feltham
Stephanie M Cordier
P2860
P304
35906-35915
P356
10.1074/JBC.M109.072256
P407
P577
2009-12-01T00:00:00Z