Sensing domain dynamics in protein kinase A-I{alpha} complexes by solution X-ray scattering.
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Realizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα HoloenzymePKA RIα Homodimer Structure Reveals an Intermolecular Interface with Implications for Cooperative cAMP Binding and Carney Complex DiseaseKinetics of acrylodan-labelled cAMP-dependent protein kinase catalytic subunit denaturation.Allosteric communication between cAMP binding sites in the RI subunit of protein kinase A revealed by NMRUsing Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIα activation in response to cAMP bindingMapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα.Communication between tandem cAMP binding domains in the regulatory subunit of protein kinase A-Ialpha as revealed by domain-silencing mutations.Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG).Molecular Simulations Reveal an Unresolved Conformation of the Type IA Protein Kinase A Regulatory Subunit and Suggest Its Role in the cAMP Regulatory Mechanism.Role of arginine 209 in the conformational transition of the protein kinase A regulatory subunit RIα A-domain.Switching of the folding-energy landscape governs the allosteric activation of protein kinase A
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Sensing domain dynamics in protein kinase A-I{alpha} complexes by solution X-ray scattering.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on December 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Sensing domain dynamics in pro ...... by solution X-ray scattering.
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Sensing domain dynamics in pro ...... by solution X-ray scattering.
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Sensing domain dynamics in pro ...... by solution X-ray scattering.
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Sensing domain dynamics in pro ...... by solution X-ray scattering.
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Sensing domain dynamics in pro ...... by solution X-ray scattering.
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Sensing domain dynamics in pro ...... by solution X-ray scattering.
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Sensing domain dynamics in pro ...... s by solution X-ray scattering
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Cecilia Y Cheng
Susan S Taylor
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35916-35925
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10.1074/JBC.M109.059493
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P577
2009-12-01T00:00:00Z