Molecular Interactions between HIV-1 integrase and the two viral DNA ends within the synaptic complex that mediates concerted integration. - Wikidata - awgldk - TriplyDB

Molecular Interactions between HIV-1 integrase and the two viral DNA ends within the synaptic complex that mediates concerted integration.

Molecular Interactions between HIV-1 integrase and the two viral DNA ends within the synaptic complex that mediates concerted integration.

http://www.wikidata.org/entity/Q37468745

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Multifunctional facets of retrovirus integrase Engineered hyperactive integrase for concerted HIV-1 DNA integration Retroviral DNA Integration Virus-like attachment sites and plastic CpG islands:landmarks of diversity in plant Del retrotransposons Solution conformations of prototype foamy virus integrase and its stable synaptic complex with U5 viral DNA.Critical appraisal of elvitegravir in the treatment of HIV-1/AIDS.Rous sarcoma virus synaptic complex capable of concerted integration is kinetically trapped by human immunodeficiency virus integrase strand transfer inhibitors.Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome Structural properties of HIV integrase. Lens epithelium-derived growth factor oligomers.Retrovirus Integrase-DNA Structure Elucidates Concerted Integration Mechanisms.Physical trapping of HIV-1 synaptic complex by different structural classes of integrase strand transfer inhibitors.Retroviral integrase proteins and HIV-1 DNA integration Retroviral Integrase Structure and DNA Recombination Mechanism Allosteric inhibitor development targeting HIV-1 integrase.HIV-1 integrase strand transfer inhibitors stabilize an integrase-single blunt-ended DNA complex Nucleoprotein intermediates in HIV-1 DNA integration visualized by atomic force microscopy The HIV-1 integrase monomer induces a specific interaction with LTR DNA for concerted integration.Raltegravir in HIV-1 infection: Safety and Efficacy in Treatment-naïve Patients.DNA requirements for assembly and stability of HIV-1 intasomes Interaction between Reverse Transcriptase and Integrase Is Required for Reverse Transcription during HIV-1 Replication.Structural biology of retroviral DNA integration.Sites of retroviral DNA integration: From basic research to clinical applications Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.Multimodal mechanism of action of allosteric HIV-1 integrase inhibitors.HIV-1 Integrase-DNA Recognition Mechanisms.HIV-1 latency in monocytes/macrophages HIV-1 integrase multimerization as a therapeutic target.A C-terminal "Tail" Region in the Rous Sarcoma Virus Integrase Provides High Plasticity of Functional Integrase Oligomerization during Intasome Assembly.Retroviral integrase protein and intasome nucleoprotein complex structures.Retroviral intasomes arising.Correlation of recombinant integrase activity and functional preintegration complex formation during acute infection by replication-defective integrase mutant human immunodeficiency virus.

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Molecular Interactions between HIV-1 integrase and the two viral DNA ends within the synaptic complex that mediates concerted integration.

http://www.wikidata.org/entity/Q37468745

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 09 April 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Molecular Interactions between ...... ediates concerted integration.

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Molecular Interactions between ...... ediates concerted integration.

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J.JMB.2009.04.007

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Journal of Molecular Biology

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Molecular Interactions between ...... ediates concerted integration.

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Ajaykumar C Vora

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Duane P Grandgenett

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Krishan K Pandey

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Sibes Bera

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P2860

HIV-1 integrase crosslinked oligomers are active in vitro

Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition

Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein.

High-resolution structure of the catalytic domain of avian sarcoma virus integrase

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes.

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

Structure and function of HIV-1 integrase.

Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding

In vivo analysis of retroviral integrase structure and function.

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183-198

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10.1016/J.JMB.2009.04.007

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19362096

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