Multiple conformations of full-length p53 detected with single-molecule fluorescence resonance energy transfer.
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Constructing ensembles for intrinsically disordered proteinsMultiply labeling proteins for studies of folding and stabilityModulation of the disordered conformational ensembles of the p53 transactivation domain by cancer-associated mutationsSlow unfolded-state structuring in Acyl-CoA binding protein folding revealed by simulation and experimentDNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions.Characterizing functional domains for TIM-mediated enveloped virus entryThe Stress-response protein prostate-associated gene 4, interacts with c-Jun and potentiates its transactivation.Protein dynamics via computational microscope.Near-membrane ensemble elongation in the proline-rich LRP6 intracellular domain may explain the mysterious initiation of the Wnt signaling pathway.Expanding the proteome: disordered and alternatively folded proteins.Variation in the mechanical unfolding pathway of p53DBD induced by interaction with p53 N-terminal region or DNA.Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNAA single-molecule characterization of p53 search on DNAVisualization of the nanospring dynamics of the IkappaBalpha ankyrin repeat domain in real timeSingle-molecule tools elucidate H2A.Z nucleosome composition.Domain-domain interactions in full-length p53 and a specific DNA complex probed by methyl NMR spectroscopy.2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells.The C-terminal domain of the bacteriophage T4 terminase docks on the prohead portal clip region during DNA packaging.Shedding light on protein folding landscapes by single-molecule fluorescence.FRET and FCS--friends or foes?Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery.A co-expression strategy to achieve labeling of individual subunits within a dimeric protein for single molecule analysis.Structural Evolution and Dynamics of the p53 Proteins.The principle of conformational signaling.How p53 wields the scales of fate: arrest or death?Long-range modulation of chain motions within the intrinsically disordered transactivation domain of tumor suppressor p53.High-resolution structural characterization of Noxa, an intrinsically disordered protein, by microsecond molecular dynamics simulations.Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53.Kinetics of fast changing intramolecular distance distributions obtained by combined analysis of FRET efficiency kinetics and time-resolved FRET equilibrium measurements.Molecular dynamics of the full-length p53 monomer.Aromatic residues link binding and function of intrinsically disordered proteins.One-Dimensional Search Dynamics of Tumor Suppressor p53 Regulated by a Disordered C-Terminal Domain.Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism
P2860
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P2860
Multiple conformations of full-length p53 detected with single-molecule fluorescence resonance energy transfer.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
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2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
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name
Multiple conformations of full ...... nce resonance energy transfer.
@en
Multiple conformations of full ...... nce resonance energy transfer.
@nl
type
label
Multiple conformations of full ...... nce resonance energy transfer.
@en
Multiple conformations of full ...... nce resonance energy transfer.
@nl
prefLabel
Multiple conformations of full ...... nce resonance energy transfer.
@en
Multiple conformations of full ...... nce resonance energy transfer.
@nl
P2093
P2860
P50
P356
P1476
Multiple conformations of full ...... nce resonance energy transfer.
@en
P2093
Angus J Bain
Daven A Armoogum
Elisha Haas
Fang Huang
Nick Nicolaou
Richard J Marsh
Sridharan Rajagopalan
P2860
P304
20758-20763
P356
10.1073/PNAS.0909644106
P407
P577
2009-11-20T00:00:00Z