The slow-aging growth hormone receptor/binding protein gene-disrupted (GHR-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty
about
Preservation of blood glucose homeostasis in slow-senescing somatotrophism-deficient mice subjected to intermittent fasting begun at middle or old age.Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow agingDo altered energy metabolism or spontaneous locomotion 'mediate' decelerated senescence?Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice.Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.
P2860
The slow-aging growth hormone receptor/binding protein gene-disrupted (GHR-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The slow-aging growth hormone ...... t neuromusculoskeletal frailty
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The slow-aging growth hormone receptor/binding protein gene-disrupted
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type
label
The slow-aging growth hormone ...... t neuromusculoskeletal frailty
@en
The slow-aging growth hormone receptor/binding protein gene-disrupted
@nl
prefLabel
The slow-aging growth hormone ...... t neuromusculoskeletal frailty
@en
The slow-aging growth hormone receptor/binding protein gene-disrupted
@nl
P2093
P2860
P1433
P1476
The slow-aging growth hormone ...... t neuromusculoskeletal frailty
@en
P2093
Andrzej Bartke
Dustin J Rickman
John J Kopchick
P2860
P304
P356
10.1007/S11357-013-9551-X
P577
2013-07-04T00:00:00Z