Class II major histocompatibility complex molecules of murine dendritic cells: synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture.
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Inhibitory p41 isoform of invariant chain and its potential target enzymes cathepsins L and H in distinct populations of macrophages in human lymph nodesMajor histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin LEfficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alphaDefective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expressionPolarized expression of CD74 by gastric epithelial cells.Proteolysis of major histocompatibility complex class II-associated invariant chain is regulated by the alternatively spliced gene product, p41.The 60-kDa heat shock protein modulates allograft rejection.HIV-1 lentiviral vector immunogenicity is mediated by Toll-like receptor 3 (TLR3) and TLR7.Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartmentsDermal toxicity: alternative methods for risk assessmentSynthesis, stability, and subcellular distribution of major histocompatibility complex class II molecules in Langerhans cells infected with Leishmania major.Antigen-pulsed dendritic cells can efficiently induce an antibody response in vivo.Identification of proliferating dendritic cell precursors in mouse blood.Efficient endosomal localization of major histocompatibility complex class II-invariant chain complexes requires multimerization of the invariant chain targeting sequence.Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo.Invariant chain controls the activity of extracellular cathepsin L.Endocytosis by antigen presenting cells: dendritic cells are as endocytically active as other antigen presenting cellsExposing the Specific Roles of the Invariant Chain Isoforms in Shaping the MHC Class II Peptidome.Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin.CD74: an emerging opportunity as a therapeutic target in cancer and autoimmune disease.The endocytic activity of dendritic cells.Physiological functions of endosomal proteolysis.Purification of intracellular compartments involved in antigen processing: a new method based on magnetic sorting.Immunocompetent astrocytes and microglia display major differences in the processing of the invariant chain and in the expression of active cathepsin L and cathepsin S.Inhibitory fragment from the p41 form of invariant chain can regulate activity of cysteine cathepsins in antigen presentation.Lysosomal cathepsin B plays an important role in antigen processing, while cathepsin D is involved in degradation of the invariant chain inovalbumin-immunized mice.Differential susceptibility to CD95 (Apo-1/Fas) and MHC class II-induced apoptosis during murine dendritic cell development.Thyroglobulin type-I-like domains in invariant chain fusion proteins mediate resistance to cathepsin L digestion.Differential regulation of MHC II and invariant chain expression during maturation of monocyte-derived dendritic cells.
P2860
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P2860
Class II major histocompatibility complex molecules of murine dendritic cells: synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Class II major histocompatibil ...... e down-regulated upon culture.
@en
Class II major histocompatibil ...... e down-regulated upon culture.
@nl
type
label
Class II major histocompatibil ...... e down-regulated upon culture.
@en
Class II major histocompatibil ...... e down-regulated upon culture.
@nl
prefLabel
Class II major histocompatibil ...... e down-regulated upon culture.
@en
Class II major histocompatibil ...... e down-regulated upon culture.
@nl
P2093
P2860
P356
P1476
Class II major histocompatibil ...... e down-regulated upon culture.
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.8.3014
P407
P577
1991-04-01T00:00:00Z