Sustained hypoxia leads to the emergence of cells with enhanced growth, migratory, and promitogenic potentials within the distal pulmonary artery wall.
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Sex hormones and vascular protection in pulmonary arterial hypertension.Adenosine A1 receptors promote vasa vasorum endothelial cell barrier integrity via Gi and Akt-dependent actin cytoskeleton remodelingSignificance of main pulmonary artery dilation on imaging studies.The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes.Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunctionVaricella zoster virus vasculopathy: analysis of virus-infected arteries.Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertensionHemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration.Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension.COPD/emphysema: The vascular story.Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia.Silencing of sodium-hydrogen exchanger 1 attenuates the proliferation, hypertrophy, and migration of pulmonary artery smooth muscle cells via E2F1Circulating fibrocytes are increased in children and young adults with pulmonary hypertension.Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.Interplay of macrophages and T cells in the lung vasculature.Distinct responses to hypoxia in subpopulations of distal pulmonary artery cells contribute to pulmonary vascular remodeling in emphysema.Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.Hypoxia-induced endothelial CX3CL1 triggers lung smooth muscle cell phenotypic switching and proliferative expansionMAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension.Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling.Antagonism of stem cell factor/c-kit signaling attenuates neonatal chronic hypoxia-induced pulmonary vascular remodeling.Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.Loss of Twist1 in the Mesenchymal Compartment Promotes Increased Fibrosis in Experimental Lung Injury by Enhanced Expression of CXCL12Hypoxic pulmonary hypertension of the newborn.The adventitia: Essential role in pulmonary vascular remodeling.Smooth muscle cell hypertrophy, proliferation, migration and apoptosis in pulmonary hypertension.Lungs at high-altitude: genomic insights into hypoxic responses.Effect of endothelin receptor antagonist bosentan on chronic hypoxia-induced inflammation and chemoafferent neuron adaptation in rat carotid body.Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid.A translational preclinical model of interstitial pulmonary fibrosis and pulmonary hypertension: mechanistic pathways driving disease pathophysiologyPro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension.Dynamic and Diverse Changes in the Functional Properties of Vascular Smooth Muscle Cells in Pulmonary Hypertension.Cyp2c44 gene disruption is associated with increased hematopoietic stem cells: implication in chronic hypoxia-induced pulmonary hypertension.Cyp2c44-mediated decrease of 15-HETE exacerbates pulmonary hypertension.C-kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension.
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P2860
Sustained hypoxia leads to the emergence of cells with enhanced growth, migratory, and promitogenic potentials within the distal pulmonary artery wall.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Sustained hypoxia leads to the ...... distal pulmonary artery wall.
@en
Sustained hypoxia leads to the ...... distal pulmonary artery wall.
@nl
type
label
Sustained hypoxia leads to the ...... distal pulmonary artery wall.
@en
Sustained hypoxia leads to the ...... distal pulmonary artery wall.
@nl
prefLabel
Sustained hypoxia leads to the ...... distal pulmonary artery wall.
@en
Sustained hypoxia leads to the ...... distal pulmonary artery wall.
@nl
P2093
P2860
P1476
Sustained hypoxia leads to the ...... distal pulmonary artery wall.
@en
P2093
Danielle L Burke
Derek Strassheim
Joanna L Sylman
Kurt R Stenmark
Maria G Frid
Meena Gnanasekharan
Miguel Fragoso
P2860
P304
P356
10.1152/AJPLUNG.90611.2008
P577
2009-09-18T00:00:00Z