TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies.
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Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancerSuperior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivityNovel HTS strategy identifies TRAIL-sensitizing compounds acting specifically through the caspase-8 apoptotic axis.Beyond cell death - antiapoptotic Bcl-2 proteins regulate migration and invasion of colorectal cancer cells in vitroA New Player in the Development of TRAIL Based Therapies for Hepatocarcinoma Treatment: ATM Kinase.Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling.Overexpression of c-Jun contributes to sorafenib resistance in human hepatoma cell lines.Targeting the apoptotic pathway in chondrosarcoma using recombinant human Apo2L/TRAIL (dulanermin), a dual proapoptotic receptor (DR4/DR5) agonist.Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody.HBV polymerase overexpression due to large core gene deletion enhances hepatoma cell growth by binding inhibition of microRNA-100.Targeting cell death signaling in colorectal cancer: current strategies and future perspectives.Targeting microRNAs to modulate TRAIL-induced apoptosis of cancer cells.Moving towards personalised therapy in patients with hepatocellular carcinoma: the role of the microenvironment.A randomized, double-blind, placebo-controlled phase II study to assess the efficacy and safety of mapatumumab with sorafenib in patients with advanced hepatocellular carcinoma.ABT-263 sensitizes TRAIL-resistant hepatocarcinoma cells by downregulating the Bcl-2 family of anti-apoptotic protein.shRNA-mediated silencing of Gli2 gene inhibits proliferation and sensitizes human hepatocellular carcinoma cells towards TRAIL-induced apoptosis.Sorafenib perpetuates cellular anticancer effector functions by modulating the crosstalk between macrophages and natural killer cells.Cancer vaccines and immunotherapeutic approaches in hepatobiliary and pancreatic cancers.Knockdown of HMGA1 expression by short/small hairpin RNA inhibits growth of ovarian carcinoma cells.
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P2860
TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
TRAIL-induced apoptosis of hep ...... gmented by targeted therapies.
@en
TRAIL-induced apoptosis of hep ...... gmented by targeted therapies.
@nl
type
label
TRAIL-induced apoptosis of hep ...... gmented by targeted therapies.
@en
TRAIL-induced apoptosis of hep ...... gmented by targeted therapies.
@nl
prefLabel
TRAIL-induced apoptosis of hep ...... gmented by targeted therapies.
@en
TRAIL-induced apoptosis of hep ...... gmented by targeted therapies.
@nl
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P2860
P356
P1476
TRAIL-induced apoptosis of hep ...... ugmented by targeted therapies
@en
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Bruno-Christian Koehler
Henning Schulze-Bergkamen
Marcus Schuchmann
Peter-R Galle
Regina-Johanna Boger
Steffen Heeger
Toni Urbanik
P2860
P304
P356
10.3748/WJG.15.5924
P407
P50
P577
2009-12-01T00:00:00Z