Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme.
about
Infection of HLA-DR1 transgenic mice with a human isolate of influenza a virus (H1N1) primes a diverse CD4 T-cell repertoire that includes CD4 T cells with heterosubtypic cross-reactivity to avian (H5N1) influenza virus.Endogenous antigen presentation by autoantigen-transfected Epstein-Barr virus-lymphoblastoid cells. I. Generation of human thyroid peroxidase-reactive T cells and their T cell receptor repertoireRole of heat shock proteins in protection from and pathogenesis of infectious diseases.Expression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteins"Troy-bodies": recombinant antibodies that target T cell epitopes to antigen presenting cells.Diversity in MHC class II antigen presentation.Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules.Measles virus transmembrane fusion protein synthesized de novo or presented in immunostimulating complexes is endogenously processed for HLA class I- and class II-restricted cytotoxic T cell recognition.Endogenous altered peptide ligands can affect peripheral T cell responses.Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice.A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex.Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigensPresentation of peptide antigens by mouse CD1 requires endosomal localization and protein antigen processing.Beyond the classical: influenza virus and the elucidation of alternative MHC class II-restricted antigen processing pathways.Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.Processing and presentation of idiotypes to MHC-restricted T cells.Exogenous peptides compete for the presentation of endogenous antigens to major histocompatibility complex class II-restricted T cells.Processing of the DRB1*1103-restricted measles virus nucleoprotein determinant 185-199 in the endosomal compartment.Insufficient autoantigen presentation and failure of tolerance in a mouse model of rheumatoid arthritis.Major histocompatibility complex class II-dependent unfolding, transport, and degradation of endogenous proteins.
P2860
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P2860
Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Class II-restricted presentati ...... terminant of hen egg lysozyme.
@en
Class II-restricted presentati ...... terminant of hen egg lysozyme.
@nl
type
label
Class II-restricted presentati ...... terminant of hen egg lysozyme.
@en
Class II-restricted presentati ...... terminant of hen egg lysozyme.
@nl
prefLabel
Class II-restricted presentati ...... terminant of hen egg lysozyme.
@en
Class II-restricted presentati ...... terminant of hen egg lysozyme.
@nl
P2093
P2860
P356
P1476
Class II-restricted presentati ...... terminant of hen egg lysozyme.
@en
P2093
Goodnow CC
Kjer-Nielsen L
McCluskey J
P2860
P304
P356
10.1073/PNAS.88.8.3290
P407
P577
1991-04-01T00:00:00Z