IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo
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The Timing of T Cell Priming and CyclingDiacylglycerol Kinases in T Cell Tolerance and Effector FunctionListeria monocytogenes: a model pathogen to study antigen-specific memory CD8 T cell responsesType I Interferons Induce T Regulatory 1 Responses and Restrict Humoral Immunity during Experimental MalariaType I IFN signaling facilitates the development of IL-10-producing effector CD8+ T cells during murine influenza virus infection.CD70 and IFN-1 selectively induce eomesodermin or T-bet and synergize to promote CD8+ T-cell responses.Antiviral Functions of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific IgG Antibodies: Effects of Antiretroviral Therapy and Implications for Therapeutic HIV-1 Vaccine Design.Unraveling the convoluted biological roles of type I interferons in infection and immunity: a way forward for therapeutics and vaccine design.CD8 T cells in innate immune responses: using STAT4-dependent but antigen-independent pathways to gamma interferon during viral infection.The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens.Smad4 promotes differentiation of effector and circulating memory CD8 T cells but is dispensable for tissue-resident memory CD8 T cellsAntigen expression determines adenoviral vaccine potency independent of IFN and STING signaling.Diet-induced obesity does not impact the generation and maintenance of primary memory CD8 T cellsIRF3 deficiency impacts granzyme B expression and maintenance of memory T cell function in response to viral infection.Downregulation of Cytokines and Chemokines by GB Virus C After Transmission Via Blood Transfusion in HIV-Positive Blood RecipientsThe Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses.Transforming growth factor-β signaling is constantly shaping memory T-cell population.Interaction of astrocytes and T cells in physiological and pathological conditionsMaking many from few: IL-12p40 as a model for the combinatorial assembly of heterodimeric cytokines.Inflammatory IL-15 is required for optimal memory T cell responses.Enhancing Dendritic Cell-based Immunotherapy with IL-2/Monoclonal Antibody Complexes for Control of Established Tumors.STAT2 Is Required for TLR-Induced Murine Dendritic Cell Activation and Cross-PresentationEpstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.Regulatory and activated effector T cells in chronic hepatitis C virus: Relation to autoimmunity.pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion.T-cell stimuli independently sum to regulate an inherited clonal division fate.Responses to LPS boost effector CD8 T-cell accumulation outside of signals 1 and 2.Influence of time and number of antigen encounters on memory CD8 T cell development.Type I interferons as regulators of human antigen presenting cell functions.Interferon regulatory factor 3 in adaptive immune responses.Impact of Inflammatory Cytokines on Effector and Memory CD8+ T Cells.Tim-3-expressing macrophages are functionally suppressed and expanded in oral squamous cell carcinoma due to virus-induced Gal-9 expression.Manipulating Memory CD8 T Cell Numbers by Timed Enhancement of IL-2 Signals.Mesothelin-specific cell-based vaccine generates antigen-specific immunity and potent antitumor effects by combining with IL-12 immunomodulator.Environmental cues orchestrate regional immune surveillance and protection by pulmonary CTLs.Reducing CD73 expression by IL1β-Programmed Th17 cells improves immunotherapeutic control of tumors.IL-21 Is Important for Induction of KLRG1+ Effector CD8 T Cells during Acute Intracellular InfectionUnexpected positive control of NFκB and miR-155 by DGKα and ζ ensures effector and memory CD8+ T cell differentiation.IL-12 Signals through the TCR To Support CD8 Innate Immune Responses.Herpesvirus-Associated Lymphadenitis Distorts Fibroblastic Reticular Cell Microarchitecture and Attenuates CD8 T Cell Responses to Neurotropic Infection in Mice Lacking the STING-IFNα/β Defense Pathways.
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IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 23 December 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
IL-12 and type I interferon pr ...... ffinity IL-2 signaling in vivo
@en
IL-12 and type I interferon pr ...... finity IL-2 signaling in vivo.
@nl
type
label
IL-12 and type I interferon pr ...... ffinity IL-2 signaling in vivo
@en
IL-12 and type I interferon pr ...... finity IL-2 signaling in vivo.
@nl
prefLabel
IL-12 and type I interferon pr ...... ffinity IL-2 signaling in vivo
@en
IL-12 and type I interferon pr ...... finity IL-2 signaling in vivo.
@nl
P2093
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P1476
IL-12 and type I interferon pr ...... ffinity IL-2 signaling in vivo
@en
P2093
Gabriel R Starbeck-Miller
Hai-Hui Xue
John T Harty
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P304
P356
10.1084/JEM.20130901
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P577
2013-12-23T00:00:00Z