Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.

Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.

Item
http://www.wikidata.org/entity/Q37483993
Development and inter-laboratory validation of unlabeled probe melting curve analysis for detection of JAK2 V617F mutation in polycythemia vera.Structure-based design of oxygen-linked macrocyclic kinase inhibitors: discovery of SB1518 and SB1578, potent inhibitors of Janus kinase 2 (JAK2) and Fms-like tyrosine kinase-3 (FLT3).Benzoxathiol derivative BOT-4-one suppresses L540 lymphoma cell survival and proliferation via inhibition of JAK3/STAT3 signaling.Combination treatment in vitro with Nutlin, a small-molecule antagonist of MDM2, and pegylated interferon-α 2a specifically targets JAK2V617F-positive polycythemia vera cellsCombined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors.Recent developments on JAK2 inhibitors: a patent review.Experimental therapeutics for patients with myeloproliferative neoplasias.PCM1-JAK2-fusion: a potential treatment target in myelodysplastic-myeloproliferative and other hemato-lymphoid neoplasms.Targeting transcription factor Stat5a/b as a therapeutic strategy for prostate cancer.Targeting the DFG-in kinase conformation: a new trend emerging from a patent analysis.Beyond transcription factors: how oncogenic signalling reshapes the epigenetic landscape.Development and validation of a tetra-primer amplification refractory mutation system-polymerase chain reaction combined with melting analysis-assay for clinical JAK2 V617F mutation detection.
P2860

Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.

Item
http://www.wikidata.org/entity/Q37483993
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.
@en
Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.
@nl
type
label
Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.
@en
Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.
@nl
prefLabel
Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.
@en
Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932