The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease.
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Endoplasmic Reticulum Stress and Ethanol NeurotoxicityGenetics of Progressive Supranuclear PalsyThe unfolded protein response in neurodegenerative diseases: a neuropathological perspectiveReview: Modulating the unfolded protein response to prevent neurodegeneration and enhance memoryRepurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice.Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy.From immunobiology to β-cell biology: the changing perspective on type 1 diabetesPERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia.Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology.PERK activation mitigates tau pathology in vitro and in vivo.Prions: generation and spread versus neurotoxicity.The role of endoplasmic reticulum stress in human pathology.Unfolding the promise of translational targeting in neurodegenerative disease.ER stress and the unfolded protein response in neurodegeneration.Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology.Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).The unfolded protein response: mechanisms and therapy of neurodegeneration.Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity.The role of endoplasmic reticulum stress in neurodegenerative disease.Modulation of AβPP and GSK3β by Endoplasmic Reticulum Stress and Involvement in Alzheimer's Disease.Fine-tuning PERK signaling for neuroprotection.IRE1 signaling exacerbates Alzheimer's disease pathogenesis.Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.Bushen-Yizhi formula ameliorates cognitive dysfunction through SIRT1/ER stress pathway in SAMP8 mice.Combined Diffusion Tensor Imaging and Apparent Transverse Relaxation Rate Differentiate Parkinson Disease and Atypical Parkinsonism.Exposure to BMAA mirrors molecular processes linked to neurodegenerative disease.Regulation of mRNA Translation in Neurons-A Matter of Life and Death.Early and Selective Activation and Subsequent Alterations to the Unfolded Protein Response in Down Syndrome Mouse Models.The Prenylflavonoid Xanthohumol Reduces Alzheimer-Like Changes and Modulates Multiple Pathogenic Molecular Pathways in the Neuro2a/APPswe Cell Model of AD.Wolfram syndrome: MAMs' connection?Exercise Mitigates Alcohol Induced Endoplasmic Reticulum Stress Mediated Cognitive Impairment through ATF6-Herp Signaling.The contribution of mutant GBA to the development of Parkinson disease in Drosophila.Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum.Replication of progressive supranuclear palsy genome-wide association study identifies SLCO1A2 and DUSP10 as new susceptibility lociOverexpression of quality control proteins reduces prion conversion in prion-infected cells
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P2860
The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The unfolded protein response ...... palsy and Alzheimer's disease.
@en
The unfolded protein response ...... palsy and Alzheimer's disease.
@nl
type
label
The unfolded protein response ...... palsy and Alzheimer's disease.
@en
The unfolded protein response ...... palsy and Alzheimer's disease.
@nl
prefLabel
The unfolded protein response ...... palsy and Alzheimer's disease.
@en
The unfolded protein response ...... palsy and Alzheimer's disease.
@nl
P2093
P2860
P356
P1476
The unfolded protein response ...... palsy and Alzheimer's disease.
@en
P2093
Adam C Naj
Bernie Devlin
Gerard D Schellenberg
Lauren D Stutzbach
PSP Genetics Study Group
Roger Albin
Sharon X Xie
Sid Gilman
Virginia M Y Lee
P2860
P2888
P356
10.1186/2051-5960-1-31
P577
2013-07-06T00:00:00Z