MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation
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PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformationPTEN represses RNA Polymerase I transcription by disrupting the SL1 complexThe RNA polymerase I transcription machineryCentromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromereEmerging Roles for Maf1 beyond the Regulation of RNA Polymerase III ActivityNuclear PI3K signaling in cell growth and tumorigenesisLAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesisNucleolar stress is an early response to myocardial damage involving nucleolar proteins nucleostemin and nucleophosminUBF levels determine the number of active ribosomal RNA genes in mammalsInhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53Identification of functional networks of estrogen- and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer.Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental SignalingStructure and epigenetics of nucleoli in comparison with non-nucleolar compartmentsThe pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma.Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes.The HBx oncoprotein of hepatitis B virus potentiates cell transformation by inducing c-Myc-dependent expression of the RNA polymerase I transcription factor UBFDirect regulation of rRNA transcription by fibroblast growth factor 2Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesisNucleolar stress with and without p53.Inflammatory disease and lymphomagenesis caused by deletion of the Myc antagonist Mnt in T cells.Dysregulation of RNA polymerase I transcription during disease.c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiationPNRC accumulates in the nucleolus by interaction with B23/nucleophosmin via its nucleolar localization sequenceTcof1/Treacle is required for neural crest cell formation and proliferation deficiencies that cause craniofacial abnormalities.The role of Myc-induced protein synthesis in cancer.Identification of AMP-activated protein kinase targets by a consensus sequence search of the proteome.Downregulation of rRNA transcription triggers cell differentiation.RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.Genome wide mapping of UBF binding-sites in mouse and human cell lines.Drosophila Low Temperature Viability Protein 1 (LTV1) Is Required for Ribosome Biogenesis and Cell Growth Downstream of Drosophila Myc (dMyc)RNA-polymerase-I-directed rDNA transcription, life and works.Depletion of NEAT1 lncRNA attenuates nucleolar stress by releasing sequestered P54nrb and PSF to facilitate c-Myc translation.Analysis of histone modifications at human ribosomal DNA in liver cancer cellDepletion of the cisplatin targeted HMGB-box factor UBF selectively induces p53-independent apoptotic death in transformed cells.Drosophila growth and development in the absence of dMyc and dMnt.Targeting MYC in cancer therapy: RNA processing offers new opportunities.Genomic characterization of the mouse ribosomal DNA locusThe Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer.Therapeutic Approaches Targeting MYC-Driven Prostate Cancer
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MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 29 July 2004
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation
@en
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation.
@nl
type
label
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation
@en
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation.
@nl
prefLabel
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation
@en
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation.
@nl
P2093
P2860
P50
P356
P1433
P1476
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation
@en
P2093
Anna Jenkins
Hayley Snelling
Katherine M Hannan
Kerith Sharkey
Manuela Palatsides
Meaghan Wall
Richard B Pearson
Yves Brandenburger
P2860
P304
P356
10.1038/SJ.EMBOJ.7600335
P407
P577
2004-07-29T00:00:00Z