Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes. - Wikidata - awgldk - TriplyDB

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

http://www.wikidata.org/entity/Q37491359

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Cancer Stem Cell Hierarchy in Glioblastoma Multiforme Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone Engagement of cellular prion protein with the co-chaperone Hsp70/90 organizing protein regulates the proliferation of glioblastoma stem-like cells.Metabolomics of Therapy Response in Preclinical Glioblastoma: A Multi-Slice MRSI-Based Volumetric Analysis for Noninvasive Assessment of Temozolomide Treatment Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas OECI-EACR precision medicine for cancer: Conference report 1-4 March 2015, Luxembourg.Coexpression analysis of CD133 and CD44 identifies proneural and mesenchymal subtypes of glioblastoma multiforme.Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs.From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity.Intratumoral heterogeneity in glioblastoma: don't forget the peritumoral brain zone.Aggressive invasion is observed in CD133(-)/A2B5(+) glioma-initiating cells.Genomic amplification of 9p24.1 targeting JAK2, PD-L1, and PD-L2 is enriched in high-risk triple negative breast cancer.Targeted Proteomics to Assess the Response to Anti-Angiogenic Treatment in Human Glioblastoma (GBM).Heterogeneous glioblastoma cell cross-talk promotes phenotype alterations and enhanced drug resistance.Transmembrane protein CD9 is glioblastoma biomarker, relevant for maintenance of glioblastoma stem cells.Chromosomal Instability Affects the Tumorigenicity of Glioblastoma Tumor-Initiating Cells.Temozolomide promotes genomic and phenotypic changes in glioblastoma cells.Cancer Stem Cells in Glioblastoma Multiforme.Cancer stem cells, a fuzzy evolving concept: a cell population or a cell property?Glioma: experimental models and reality.Adult neurogenesis and glial oncogenesis: when the process fails.Immunotherapy with dendritic cells loaded with glioblastoma stem cells: from preclinical to clinical studies.The Impact of the Tumor Microenvironment on the Properties of Glioma Stem-Like Cells.Multiple Subsets of Brain Tumor Initiating Cells Coexist in Glioblastoma.The taxonomy of brain cancer stem cells: what's in a name?Immune and viral therapies for malignant primary brain tumors.Targeting Malignant Brain Tumors with Antibodies.Genetic Evolution of Glioblastoma Stem-Like Cells From Primary to Recurrent Tumor.Immunotherapy for brain tumors: understanding early successes and limitations.Molecular Subgroups of Glioblastoma- an Assessment by Immunohistochemical Markers.Gauging heterogeneity in primary versus recurrent glioblastoma.Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma.Longevity-Related Gene Transcriptomic Signature in Glioblastoma Multiforme.Immunophenotypic characterization of human glioblastoma stem cells: correlation with clinical outcome.MicroRNA expression signatures and their correlation with clinicopathological features in glioblastoma multiforme.Genomic profiling reveals distinctive molecular relapse patterns in IDH1/2 wild-type glioblastoma.

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Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

http://www.wikidata.org/entity/Q37491359

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bilimsel makale

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scientific article published on 24 October 2013

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S00401-013-1196-4

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Acta Neuropathologica

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Anaïs Oudin

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Daniel Stieber

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Elizabeth Lenkiewicz

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Frank Hertel

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Laurent Vallar

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Lisa Evers

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Michael T Barrett

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Nathalie Nicot

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Nicolaas H C Brons

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Rolf Bjerkvig

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P2860

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

The 2007 WHO classification of tumours of the central nervous system

MGMT gene silencing and benefit from temozolomide in glioblastoma.

Identification of human brain tumour initiating cells

SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma

CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

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s00401-013-1196-4

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Simone P Niclou

Anna Golebiewska

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3895194

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