Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?
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Remarkable role of indoleamine 2,3-dioxygenase and tryptophan metabolites in infectious diseases: potential role in macrophage-mediated inflammatory diseasesInflammation Models of Depression in Rodents: Relevance to Psychotropic Drug DiscoveryGenetics and biology of pancreatic ductal adenocarcinomaT Cells and Cancer: How Metabolism Shapes ImmunityTargeting the indoleamine 2,3-dioxygenase pathway in cancerThe indoleamine 2,3-dioxygenase (IDO) pathway controls allergyMyeloid-derived suppressor cells and anti-tumor T cells: a complex relationshipTrial watch: IDO inhibitors in cancer therapyBiochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogasterStructural and functional analyses of human tryptophan 2,3-dioxygenaseMolecular evolution and characterization of fungal indoleamine 2,3-dioxygenases.Targeting immune checkpoints in malignant gliomaThe Intercellular Metabolic Interplay between Tumor and Immune CellsPlasma free amino acid profiling of five types of cancer patients and its application for early detectionThe indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cellsThe secret life of NAD+: an old metabolite controlling new metabolic signaling pathways.An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular function.A biological basis for depression in pancreatic cancer.Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy.BRAF V600E in papillary thyroid carcinoma is associated with increased programmed death ligand 1 expression and suppressive immune cell infiltration.Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenaseMetabolomics for biomarker discovery in gastroenterological cancer.IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan.Analysis of lead toxicity in human cellsIndoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancerTrial Watch: Peptide-based anticancer vaccines.Substrate Oxidation by Indoleamine 2,3-Dioxygenase: EVIDENCE FOR A COMMON REACTION MECHANISMInhibitors of indoleamine 2,3-dioxygenase: a review of novel patented lead compounds.A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase.Human osteoclasts are inducible immunosuppressive cells in response to T cell-derived IFN-γ and CD40 ligand in vitroIndoleamine 2,3-diooxygenase in periaortic fat: mechanisms of inhibition of contractionProtein nitrotryptophan: formation, significance and identificationGlycogen Synthase Kinase-3β (GSK-3β) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-γ-induced Indoleamine 2,3-Dioxygenase ExpressionIFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer.Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugsReprogramming the tumor microenvironment: tumor-induced immunosuppressive factors paralyze T cells.Complete reaction mechanism of indoleamine 2,3-dioxygenase as revealed by QM/MM simulations.Immunological and nonimmunological effects of indoleamine 2,3-dioxygenase on breast tumor growth and spontaneous metastasis formationDevelopment of simultaneous analysis of tryptophan metabolites in serum and gastric juice - an investigation towards establishing a biomarker test for gastric cancer diagnosis.Several immune escape patterns in non-Hodgkin's lymphomas.
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Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Inhibitors of indoleamine-2,3- ...... we see the wood for the trees?
@en
Inhibitors of indoleamine-2,3- ...... we see the wood for the trees?
@nl
type
label
Inhibitors of indoleamine-2,3- ...... we see the wood for the trees?
@en
Inhibitors of indoleamine-2,3- ...... we see the wood for the trees?
@nl
prefLabel
Inhibitors of indoleamine-2,3- ...... we see the wood for the trees?
@en
Inhibitors of indoleamine-2,3- ...... we see the wood for the trees?
@nl
P2093
P356
P1476
Inhibitors of indoleamine-2,3- ...... we see the wood for the trees?
@en
P2093
Alfred Königsrainer
Peter Terness
Stefan Löb
P2888
P304
P356
10.1038/NRC2639
P407
P577
2009-06-01T00:00:00Z
P6179
1020939922