Mutations in herpes simplex virus glycoprotein D that prevent cell entry via nectins and alter cell tropism.
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The principal neuronal gD-type 3-O-sulfotransferases and their products in central and peripheral nervous system tissuesRandom linker-insertion mutagenesis to identify functional domains of herpes simplex virus type 1 glycoprotein BStructure of Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor Nectin-1Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesionRandom mutagenesis of the gene encoding a viral ligand for multiple cell entry receptors to obtain viral mutants altered for receptor usage.Insertion mutations in herpes simplex virus 1 glycoprotein H reduce cell surface expression, slow the rate of cell fusion, or abrogate functions in cell fusion and viral entry.Functional interaction between herpes simplex virus type 2 gD and HVEM transiently dampens local chemokine production after murine mucosal infectionCoxsackievirus A24 variant uses sialic acid-containing O-linked glycoconjugates as cellular receptors on human ocular cells.Herpes virus fusion and entry: a story with many characters.Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry.Construction and properties of a herpes simplex virus 1 designed to enter cells solely via the IL-13alpha2 receptorBispecific adapter-mediated retargeting of a receptor-restricted HSV-1 vector to CEA-bearing tumor cells.A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors.Generation of neutralizing aptamers against herpes simplex virus type 2: potential components of multivalent microbicides.Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells.Fusing structure and function: a structural view of the herpesvirus entry machinery.Separation of receptor-binding and profusogenic domains of glycoprotein D of herpes simplex virus 1 into distinct interacting proteins.The soluble amino-terminal region of HVEM mediates efficient herpes simplex virus type 1 infection of gD receptor-negative cells.Herpes B virus utilizes human nectin-1 but not HVEM or PILRα for cell-cell fusion and virus entry.HSV trafficking and development of gene therapy vectors with applications in the nervous system.Herpesvirus entry mediator on radiation-resistant cell lineages promotes ocular herpes simplex virus 1 pathogenesis in an entry-independent manner.Replication-competent herpes simplex vectors: design and applications.A herpes simplex virus 2 glycoprotein D mutant generated by bacterial artificial chromosome mutagenesis is severely impaired for infecting neuronal cells and infects only Vero cells expressing exogenous HVEM.A Herpes Simplex Virus 2 (HSV-2) gD Mutant Impaired for Neural Tropism Is Superior to an HSV-2 gD Subunit Vaccine To Protect Animals from Challenge with HSV-2.Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus.The challenge of developing a herpes simplex virus 2 vaccine.An HSV-1 gD mutant virus as an entry-impaired live virus vaccine.Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells.Ocular HSV-1 latency, reactivation and recurrent disease.Cross-regulation between herpesviruses and the TNF superfamily membersBiography of Patricia G. Spear.Use of herpes simplex virus and pseudorabies virus chimeric glycoprotein D molecules to identify regions critical for membrane fusion.HSV Recombinant Vectors for Gene Therapy.Rethinking herpes simplex virus: the way to oncolytic agents.Herpes simplex virus infects most cell types in vitro: clues to its successNectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity.Herpesvirus Entry Mediator and Ocular Herpesvirus Infection: More than Meets the Eye.Glycoproteins D of equine herpesvirus type 1 (EHV-1) and EHV-4 determine cellular tropism independently of integrins.Generation of herpesvirus entry mediator (HVEM)-restricted herpes simplex virus type 1 mutant viruses: resistance of HVEM-expressing cells and identification of mutations that rescue nectin-1 recognitionConstruction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2.
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Mutations in herpes simplex virus glycoprotein D that prevent cell entry via nectins and alter cell tropism.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 July 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mutations in herpes simplex vi ...... ectins and alter cell tropism.
@en
Mutations in herpes simplex vi ...... ectins and alter cell tropism.
@nl
type
label
Mutations in herpes simplex vi ...... ectins and alter cell tropism.
@en
Mutations in herpes simplex vi ...... ectins and alter cell tropism.
@nl
prefLabel
Mutations in herpes simplex vi ...... ectins and alter cell tropism.
@en
Mutations in herpes simplex vi ...... ectins and alter cell tropism.
@nl
P2093
P2860
P356
P1476
Mutations in herpes simplex vi ...... ectins and alter cell tropism.
@en
P2093
Cheryl R Jogger
Dawn Myscofski
Patricia G Spear
Sharmila Manoj
P2860
P304
12414-12421
P356
10.1073/PNAS.0404211101
P407
P577
2004-07-23T00:00:00Z