Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling. - Wikidata - awgldk - TriplyDB

Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling.

Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling.

http://www.wikidata.org/entity/Q37494827

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Impact of interaction between the G870A and EFEMP1 gene polymorphism on glioma risk in Chinese Han population.Fibulin-3 suppresses Wnt/β-catenin signaling and lung cancer invasion.Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas.A high-throughput cell-based Gaussia luciferase reporter assay for identifying modulators of fibulin-3 secretion Cancer stem cells maintain a hierarchy of differentiation by creating their niche Anti-EGFR function of EFEMP1 in glioma cells and patient prognosis.Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI Simvastatin Increases Fibulin-2 Expression in Human Coronary Artery Smooth Muscle Cells via RhoA/Rho-Kinase Signaling Pathway Inhibition EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway.Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis.Fibulin-3 is a novel TGF-β pathway inhibitor in the breast cancer microenvironment.Spatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone.Cell context-dependent dual effects of EFEMP1 stabilizes subpopulation equilibrium in responding to changes of in vivo growth environment Standardized orthotopic xenografts in zebrafish reveal glioma cell-line-specific characteristics and tumor cell heterogeneity.The alterations in the extracellular matrix composition guide the repair of damaged liver tissue.Efemp1 and p27(Kip1) modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models.Decrease of fibulin-3 in hepatocellular carcinoma indicates poor prognosis.Weaponizing human EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1) for 21st century cancer therapeutics.Differential proteomics analysis of low- and high-grade of astrocytoma using iTRAQ quantification EFEMP1 promotes ovarian cancer cell growth, invasion and metastasis via activated the AKT pathway.EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.Humanized chondroitinase ABC sensitizes glioblastoma cells to temozolomide.Fibulin-3-mediated inhibition of epithelial-to-mesenchymal transition and self-renewal of ALDH+ lung cancer stem cells through IGF1R signaling.p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: role in migration and invasion.Tumor-derived fibulin-3 activates pro-invasive NF-κB signaling in glioblastoma cells and their microenvironment.Fibulin-3 promotes muscle-invasive bladder cancer.The associations between common SNPs of EFEMP1 gene and glioma risk in Chinese population.Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma.TWEAK promotes migration and invasion in MEFs through a mechanism dependent on ERKs activation and Fibulin 3 down-regulation.A genome-wide association study identifies a susceptibility locus for biliary atresia on 2p16.1 within the gene EFEMP1 Extracellular Interactions between Fibulins and Transforming Growth Factor (TGF)-β in Physiological and Pathological Conditions

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Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling.

http://www.wikidata.org/entity/Q37494827

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 04 June 2012

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Fibulin-3 promotes glioma grow ...... regulation of Notch signaling.

@en

Fibulin-3 promotes glioma grow ...... regulation of Notch signaling.

@nl

type

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Fibulin-3 promotes glioma grow ...... regulation of Notch signaling.

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Fibulin-3 promotes glioma grow ...... regulation of Notch signaling.

@nl

prefLabel

Fibulin-3 promotes glioma grow ...... regulation of Notch signaling.

@en

Fibulin-3 promotes glioma grow ...... regulation of Notch signaling.

@nl

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0008-5472.CAN-12-1060

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Cancer Research

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Fibulin-3 promotes glioma grow ...... regulation of Notch signaling.

@en

P2093

Bin Hu

http://www.w3.org/2001/XMLSchema#string

Claire E Dolan

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Gerard J Nuovo

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Hosung Sim

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Joshua C Saldivar

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Maria E Mora

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Mariano S Viapiano

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Mohan S Nandhu

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Paula A Agudelo-Garcia

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Susan E Cole

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P2860

Sequence, recombinant expression and tissue localization of two novel extracellular matrix proteins, fibulin-3 and fibulin-4

EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells

The proteoglycan brevican binds to fibronectin after proteolytic cleavage and promotes glioma cell motility

Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2

Fibulin-3 is uniquely upregulated in malignant gliomas and promotes tumor cell motility and invasion

Jagged: a mammalian ligand that activates Notch1

The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands

Malignant gliomas in adults

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: a cDNA microarray analysis.

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3873-3885

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10.1158/0008-5472.CAN-12-1060

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15

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2012-06-04T00:00:00Z

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225186269

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22665268

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3896095

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