Motor neuron impairment mediated by a sumoylated fragment of the glial glutamate transporter EAAT2
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SUMOylation: Novel Neuroprotective Approach for Alzheimer's Disease?Sumoylation of critical proteins in amyotrophic lateral sclerosis: emerging pathways of pathogenesisAstrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALSSumoylation of the astroglial glutamate transporter EAAT2 governs its intracellular compartmentalizationSUMO3 modification accelerates the aggregation of ALS-linked SOD1 mutants.Early gene expression changes in spinal cord from SOD1(G93A) Amyotrophic Lateral Sclerosis animal model.Sumoylation in neurodegenerative diseases.Protein SUMOylation, an emerging pathway in amyotrophic lateral sclerosis.Molecular targets underlying SUMO-mediated neuroprotection in brain ischemia.SUMO: a (oxidative) stressed protein.Advances in cellular models to explore the pathophysiology of amyotrophic lateral sclerosis.Genetic dys-regulation of astrocytic glutamate transporter EAAT2 and its implications in neurological disorders and manganese toxicityBattling Alzheimer's Disease: Targeting SUMOylation-Mediated Pathways.HSPB1 mutations causing hereditary neuropathy in humans disrupt non-cell autonomous protection of motor neurons.The non-cell-autonomous component of ALS: new in vitro models and future challenges.Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical ApplicationsAstrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P-Glycoprotein) in endothelial cells of the blood-brain barrier in mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis.Altered Functionality, Morphology, and Vesicular Glutamate Transporter Expression of Cortical Motor Neurons from a Presymptomatic Mouse Model of Amyotrophic Lateral Sclerosis.SETX sumoylation: A link between DNA damage and RNA surveillance disrupted in AOA2.Transient ischemia induces massive nuclear accumulation of SUMO2/3-conjugated proteins in spinal cord neurons.Concise Review: The Cellular Conspiracy of Amyotrophic Lateral Sclerosis.Sumoylation: Implications for Neurodegenerative Diseases.Enzyme Complexes Important for the Glutamate-Glutamine Cycle.Transcriptional regulation of the GLAST/EAAT-1 gene in rat and man.Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS.EAAT2 and the Molecular Signature of Amyotrophic Lateral Sclerosis.
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P2860
Motor neuron impairment mediated by a sumoylated fragment of the glial glutamate transporter EAAT2
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 July 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Motor neuron impairment mediat ...... al glutamate transporter EAAT2
@en
Motor neuron impairment mediat ...... l glutamate transporter EAAT2.
@nl
type
label
Motor neuron impairment mediat ...... al glutamate transporter EAAT2
@en
Motor neuron impairment mediat ...... l glutamate transporter EAAT2.
@nl
prefLabel
Motor neuron impairment mediat ...... al glutamate transporter EAAT2
@en
Motor neuron impairment mediat ...... l glutamate transporter EAAT2.
@nl
P2093
P2860
P356
P1433
P1476
Motor neuron impairment mediat ...... al glutamate transporter EAAT2
@en
P2093
Alexey Bogush
Davide Trotti
Emily Foran
Michael Goffredo
Piera Pasinelli
Stefano Gustincich
P2860
P304
P356
10.1002/GLIA.21218
P577
2011-07-18T00:00:00Z