PRAS40: target or modulator of mTORC1 signalling and insulin action?
about
Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.Sepsis-induced alterations in protein-protein interactions within mTOR complex 1 and the modulating effect of leucine on muscle protein synthesisNuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway.Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancerEpidermal growth factor-induced vacuolar (H+)-atpase assembly: a role in signaling via mTORC1 activation.PRAS40 deregulates apoptosis in Ewing sarcoma family tumors by enhancing the insulin receptor/Akt and mTOR signaling pathwaysMolecular mechanisms of metabolic regulation by insulin in Drosophila.Limited therapeutic effect of N-acetylcysteine on hepatic insulin resistance in an experimental model of alcohol-induced steatohepatitis.mTORC1 signaling: what we still don't know.Role of PRAS40 in Akt and mTOR signaling in health and disease.Phosphorylation of interleukin (IL)-24 is required for mediating its anti-cancer activityHypoxia upregulates Rab11-family interacting protein 4 through HIF-1α to promote the metastasis of hepatocellular carcinoma.Quantitative phosphoproteomics reveals novel phosphorylation events in insulin signaling regulated by protein phosphatase 1 regulatory subunit 12A.Targeting protein kinase-b3 (akt3) signaling in melanoma.A herpesvirus kinase that masquerades as Akt: you don't have to look like Akt, to act like it.
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PRAS40: target or modulator of mTORC1 signalling and insulin action?
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
PRAS40: target or modulator of mTORC1 signalling and insulin action?
@en
PRAS40: target or modulator of mTORC1 signalling and insulin action?
@nl
type
label
PRAS40: target or modulator of mTORC1 signalling and insulin action?
@en
PRAS40: target or modulator of mTORC1 signalling and insulin action?
@nl
prefLabel
PRAS40: target or modulator of mTORC1 signalling and insulin action?
@en
PRAS40: target or modulator of mTORC1 signalling and insulin action?
@nl
P2860
P1476
PRAS40: target or modulator of mTORC1 signalling and insulin action?
@en
P2093
D Margriet Ouwens
Emmani B M Nascimento
P2860
P304
P356
10.1080/13813450902988580
P577
2009-10-01T00:00:00Z