The structures of quadruplex nucleic acids and their drug complexes.
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Recent Advances in Developing Small Molecules Targeting Nucleic AcidMolecular dynamics simulations of G-DNA and perspectives on the simulation of nucleic acid structuresAtomistic picture for the folding pathway of a hybrid-1 type human telomeric DNA G-quadruplexA G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad DynamicsSolution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic SequenceSolution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoterFluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNAStacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activityRecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5′ End-Stacked Dimeric Parallel G-QuadruplexesSolution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug DesignThe high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkagesG-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex foldStructural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere SequenceStructure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC PromoterMonomer-dimer equilibrium for the 5'-5' stacking of propeller-type parallel-stranded G-quadruplexes: NMR structural studyCharacterization of the intramolecular G-quadruplex promoting activity of Est1.Metal Cations in G-Quadruplex Folding and StabilityG-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomeTargeting human telomeric G-quadruplex DNA and inhibition of telomerase activity with [(dmb)2Ru(obip)Ru(dmb)2](4+)Finding and characterizing the complexes of drug like molecules with quadruplex DNA: combined use of an enhanced hydroxyl radical cleavage protocol and NMRComputational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengersHuman DHX9 helicase unwinds triple-helical DNA structuresConformational dynamics of the human propeller telomeric DNA quadruplex on a microsecond time scale.Cobalt(III)porphyrin to target G-quadruplex DNA.Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplexGenetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae.Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)](4).The many twists and turns of DNA: template, telomere, tool, and target.Cation involvement in telomestatin binding to g-quadruplex DNA.Nucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA"One Ring to Bind Them All"-Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles."One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.Mechanisms and implications of transcription blockage by guanine-rich DNA sequences.G-quadruplex nucleic acids and human diseaseTargeting G-quadruplexes in gene promoters: a novel anticancer strategy?Telomeres: structures in need of unwinding.Making sense of G-quadruplex and i-motif functions in oncogene promoters.Gaining insights into the small molecule targeting of the G-quadruplex in the c-MYC promoter using NMR and an allele-specific transcriptional assay.How long is too long? Effects of loop size on G-quadruplex stability.Novel G-quadruplex stabilizing agents: in-silico approach and dynamics.
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P2860
The structures of quadruplex nucleic acids and their drug complexes.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
gotara zanistî
@ku-latn
scientific article published on 30 May 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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name
The structures of quadruplex nucleic acids and their drug complexes.
@en
The structures of quadruplex nucleic acids and their drug complexes.
@nl
type
label
The structures of quadruplex nucleic acids and their drug complexes.
@en
The structures of quadruplex nucleic acids and their drug complexes.
@nl
prefLabel
The structures of quadruplex nucleic acids and their drug complexes.
@en
The structures of quadruplex nucleic acids and their drug complexes.
@nl
P1476
The structures of quadruplex nucleic acids and their drug complexes.
@en
P2093
Stephen Neidle
P304
P356
10.1016/J.SBI.2009.04.001
P577
2009-05-30T00:00:00Z