about
RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory MechanismsTemplating efficiency of naked DNA.Template-directed synthesis in 3'- and 5'-direction with reversible termination.Exploring the roles of nucleobase desolvation and shape complementarity during the misreplication of O(6)-methylguanine.Clustering of Alpers disease mutations and catalytic defects in biochemical variants reveal new features of molecular mechanism of the human mitochondrial replicase, Pol γ.Synthetic nucleotides as probes of DNA polymerase specificity.Optimal numbers of residues in linkers of DNA polymerase I, T7 primase and DNA polymerase IVVaccine-derived mutation in motif D of poliovirus RNA-dependent RNA polymerase lowers nucleotide incorporation fidelity.The kinetic and chemical mechanism of high-fidelity DNA polymerases.Walking molecules.Effects of non-catalytic, distal amino acid residues on activity of E. coli DinB (DNA polymerase IV).Nucleic acid tool enzymes-aided signal amplification strategy for biochemical analysis: status and challenges.Polymerase/DNA interactions and enzymatic activity: multi-parameter analysis with electro-switchable biosurfaces.Oxidatively activated DNA-modifying agents for selective cytotoxicity.The energetic difference between synthesis of correct and incorrect base pairs accounts for highly accurate DNA replication.Steric gate residues of Y-family DNA polymerases DinB and pol kappa are crucial for dNTP-induced conformational change.Biologically relevant oxidants cause bound proteins to readily oxidatively cross-link at Guanine.Long-range interaction networks in the function and fidelity of poliovirus RNA-dependent RNA polymerase studied by nuclear magnetic resonance.Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer.Signal-on electrochemical assay for label-free detection of TdT and BamHI activity based on grown DNA nanowire-templated copper nanoclusters.Label-free molecular beacon for real-time monitoring of DNA polymerase activity.Single-molecule imaging of DNA polymerase I (Klenow fragment) activity by atomic force microscopy.A facile graphene oxide-based DNA polymerase assay.3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase.Nucleophilic Substitution (SN 2): Dependence on Nucleophile, Leaving Group, Central Atom, Substituents, and Solvent.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mechanisms of DNA polymerases.
@en
Mechanisms of DNA polymerases.
@nl
type
label
Mechanisms of DNA polymerases.
@en
Mechanisms of DNA polymerases.
@nl
prefLabel
Mechanisms of DNA polymerases.
@en
Mechanisms of DNA polymerases.
@nl
P356
P1433
P1476
Mechanisms of DNA polymerases.
@en
P2093
Anthony J Berdis
P304
P356
10.1021/CR800530B
P577
2009-07-01T00:00:00Z