Modeling within-host effects of drugs on Plasmodium falciparum transmission and prospects for malaria elimination.
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Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmissionPrimaquine or other 8-aminoquinoline for reducing P. falciparum transmissionMathematical Modelling to Guide Drug Development for Malaria EliminationGametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient dataTransmission-blocking strategies: the roadmap from laboratory bench to the communityLead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations.Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination.Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network.Incorporating Stage-Specific Drug Action into Pharmacological Modeling of Antimalarial Drug TreatmentQuantitative, model-based estimates of variability in the generation and serial intervals of Plasmodium falciparum malaria.Quantifying the pharmacology of antimalarial drug combination therapy.The Gametocytocidal Efficacy of Different Single Doses of Primaquine with Dihydroartemisinin-piperaquine in Asymptomatic Parasite Carriers in The Gambia: A Randomized Controlled Trial.Safety and Efficacy of Adding a Single Low Dose of Primaquine to the Treatment of Adult Patients With Plasmodium falciparum Malaria in Senegal, to Reduce Gametocyte Carriage: A Randomized Controlled Trial.Modelling the benefits of long-acting or transmission-blocking drugs for reducing Plasmodium falciparum transmission by case management or by mass treatment.How important is gametocyte clearance after malaria therapy?Challenges in implementing uncomplicated malaria treatment in children: a health facility survey in rural Malawi.Fun with maths: exploring implications of mathematical models for malaria eradication.Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling.Targeting Plasmodium falciparum transmission with primaquine: same efficacy, improved safety with a lower dose?Community-led Responses for Elimination (CoRE): a study protocol for a community randomized controlled trial assessing the effectiveness of community-level, reactive focal drug administration for reducing Plasmodium falciparum infection prevalence aA Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum.Mapping multiple components of malaria risk for improved targeting of elimination interventions.Safety of single low-dose primaquine in glucose-6-phosphate dehydrogenase deficient falciparum-infected African males: Two open-label, randomized, safety trials.Primaquine or other 8-aminoquinolines for reducing Plasmodium falciparum transmission.
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Modeling within-host effects of drugs on Plasmodium falciparum transmission and prospects for malaria elimination.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Modeling within-host effects o ...... pects for malaria elimination.
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Modeling within-host effects o ...... pects for malaria elimination.
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type
label
Modeling within-host effects o ...... pects for malaria elimination.
@en
Modeling within-host effects o ...... pects for malaria elimination.
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prefLabel
Modeling within-host effects o ...... pects for malaria elimination.
@en
Modeling within-host effects o ...... pects for malaria elimination.
@nl
P2860
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Modeling within-host effects o ...... pects for malaria elimination.
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Geoffrey L Johnston
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10.1371/JOURNAL.PCBI.1003434
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2014-01-23T00:00:00Z