The signal peptide of the Junín arenavirus envelope glycoprotein is myristoylated and forms an essential subunit of the mature G1-G2 complex.
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Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern AfricaArenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategiesEnvelope glycoprotein of arenavirusesEnvelope exchange for the generation of live-attenuated arenavirus vaccinesBunyamwera orthobunyavirus glycoprotein precursor is processed by cellular signal peptidase and signal peptide peptidaseHost-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B ArenavirusesAssembly of Arenavirus Envelope Glycoprotein GPC in Detergent-Soluble Membrane MicrodomainsStructure of a Zinc-binding Domain in the Junin Virus Envelope GlycoproteinX-ray structure of the arenavirus glycoprotein GP2 in its postfusion hairpin conformationBiochemical reconstitution of hemorrhagic-fever arenavirus envelope glycoprotein-mediated membrane fusionTargeting of arenavirus RNA synthesis by a carboxamide-derivatized aromatic disulfide with virucidal activityUnique small molecule entry inhibitors of hemorrhagic fever arenaviruses.Inhibition of Lassa virus glycoprotein cleavage and multicycle replication by site 1 protease-adapted alpha(1)-antitrypsin variants.Characterization of Lassa virus glycoprotein oligomerization and influence of cholesterol on virus replication.Epidemiology and pathogenesis of Bolivian hemorrhagic fever.Novel approaches in anti-arenaviral drug developmentAn antibody directed against the fusion peptide of Junin virus envelope glycoprotein GPC inhibits pH-induced membrane fusion.Comparative analysis of disease pathogenesis and molecular mechanisms of New World and Old World arenavirus infections.Genomic and phylogenetic characterization of Merino Walk virus, a novel arenavirus isolated in South Africa.The myristate moiety and amino terminus of vaccinia virus l1 constitute a bipartite functional region needed for entryDrug discovery technologies and strategies for Machupo virus and other New World arenaviruses.Arenavirus stable signal peptide is the keystone subunit for glycoprotein complex organization.Site 1 protease is required for proteolytic processing of the glycoproteins of the South American hemorrhagic fever viruses Junin, Machupo, and Guanarito.Reverse genetics approaches to combat pathogenic arenavirusesThe curious case of arenavirus entry, and its inhibition.Role of the stable signal peptide and cytoplasmic domain of G2 in regulating intracellular transport of the Junín virus envelope glycoprotein complex.A specific interaction of small molecule entry inhibitors with the envelope glycoprotein complex of the Junín hemorrhagic fever arenavirus.Cell entry by human pathogenic arenaviruses.Identification and Mechanism of Action of a Novel Small-Molecule Inhibitor of Arenavirus Multiplication.Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike.Small-Molecule Fusion Inhibitors Bind the pH-Sensing Stable Signal Peptide-GP2 Subunit Interface of the Lassa Virus Envelope Glycoprotein.Dissection of the role of the stable signal peptide of the arenavirus envelope glycoprotein in membrane fusion.Old World arenavirus infection interferes with the expression of functional alpha-dystroglycan in the host cellA novel zinc-binding domain is essential for formation of the functional Junín virus envelope glycoprotein complex.Signal peptide requirements for lymphocytic choriomeningitis virus glycoprotein C maturation and virus infectivity.The role of proteolytic processing and the stable signal peptide in expression of the Old World arenavirus envelope glycoprotein ectodomain.Glycoprotein-Specific Antibodies Produced by DNA Vaccination Protect Guinea Pigs from Lethal Argentine and Venezuelan Hemorrhagic Fever.Arenavirus budding: a common pathway with mechanistic differences.Differential recognition of Old World and New World arenavirus envelope glycoproteins by subtilisin kexin isozyme 1 (SKI-1)/site 1 protease (S1P).Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV
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The signal peptide of the Junín arenavirus envelope glycoprotein is myristoylated and forms an essential subunit of the mature G1-G2 complex.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The signal peptide of the Juní ...... t of the mature G1-G2 complex.
@en
The signal peptide of the Juní ...... t of the mature G1-G2 complex.
@nl
type
label
The signal peptide of the Juní ...... t of the mature G1-G2 complex.
@en
The signal peptide of the Juní ...... t of the mature G1-G2 complex.
@nl
prefLabel
The signal peptide of the Juní ...... t of the mature G1-G2 complex.
@en
The signal peptide of the Juní ...... t of the mature G1-G2 complex.
@nl
P2093
P2860
P1433
P1476
The signal peptide of the Juní ...... t of the mature G1-G2 complex.
@en
P2093
Jack H Nunberg
Joanne York
Victor Romanowski
P2860
P304
10783-10792
P356
10.1128/JVI.78.19.10783-10792.2004
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P577
2004-10-01T00:00:00Z