Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes.
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Hyperpolarized magnetic resonance as a sensitive detector of metabolic functionSIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growthReduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studiesMeasurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System: A Scientific Statement From the American Heart Association.Dichloroacetate induces autophagy in colorectal cancer cells and tumours.Differential Utilization of Dietary Fatty Acids in Benign and Malignant Cells of the Prostate.(13)C-labeled biochemical probes for the study of cancer metabolism with dynamic nuclear polarization-enhanced magnetic resonance imaging.Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADHModeling non-linear kinetics of hyperpolarized [1-(13)C] pyruvate in the crystalloid-perfused rat heart.Applications of NMR spectroscopy to systems biochemistry.Hyperpolarized Sodium [1-13C]-Glycerate as a Probe for Assessing Glycolysis In Vivo.Magnetic resonance imaging with hyperpolarized agents: methods and applications.Mammalian Circadian Period, But Not Phase and Amplitude, Is Robust Against Redox and Metabolic Perturbations.Direct dynamic measurement of intracellular and extracellular lactate in small-volume cell suspensions with (13)C hyperpolarised NMR.Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response.Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters.Circadian Oscillations of NADH Redox State Using a Heterologous Metabolic Sensor in Mammalian Cells.Identification of lactate dehydrogenase as a mammalian pyrroloquinoline quinone (PQQ)-binding protein.Mitochondrial energy metabolism is required for lifespan extension by the spastic paraplegia-associated protein spartin.Cancer Metabolism and Tumor Heterogeneity: Imaging Perspectives Using MR Imaging and Spectroscopy.Retention of functional characteristics of gulathione-S-transferase and lactate dehydrogenase-A in fusion protein.Dynamic nuclear polarization facilitates monitoring of pyruvate metabolism in Trypanosoma brucei.Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio.In vivo assessment of intracellular redox state in rat liver using hyperpolarized [1-13 C]Alanine.Redox Paradox: A novel approach to therapeutics-resistant cancer.Magnetic Resonance Spectroscopy to Study Glycolytic Metabolism During Autophagy.Hyperpolarised organic phosphates as NMR reporters of compartmental pH.Spectroscopic approaches to resolving ambiguities of hyper-polarized NMR signals from different reaction cascades.Assessing the transport rate of hyperpolarized pyruvate and lactate from the intra- to the extracellular space.Determination of the in vivo NAD:NADH ratio in Saccharomyces cerevisiae under anaerobic conditions, using alcohol dehydrogenase as sensor reaction.NADH-linked metabolic plasticity of MCF-7 breast cancer cells surviving in a nutrient-deprived microenvironment.Probing treatment response of glutaminolytic prostate cancer cells to natural drugs with hyperpolarized [5-13C]glutamineRescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD
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Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Non-invasive in-cell determina ...... tions in metabolic phenotypes.
@en
Non-invasive in-cell determina ...... tions in metabolic phenotypes.
@nl
type
label
Non-invasive in-cell determina ...... tions in metabolic phenotypes.
@en
Non-invasive in-cell determina ...... tions in metabolic phenotypes.
@nl
prefLabel
Non-invasive in-cell determina ...... tions in metabolic phenotypes.
@en
Non-invasive in-cell determina ...... tions in metabolic phenotypes.
@nl
P2860
P50
P356
P1476
Non-invasive in-cell determina ...... tions in metabolic phenotypes.
@en
P2093
Jakob R Winther
P2860
P304
P356
10.1074/JBC.M113.498626
P407
P577
2013-12-03T00:00:00Z