Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic islets
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Critical role of gap junction coupled KATP channel activity for regulated insulin secretionPhase transitions in the multi-cellular regulatory behavior of pancreatic islet excitabilityIntegrated perfusion and separation systems for entrainment of insulin secretion from islets of Langerhans.Review: Microfluidic applications in metabolomics and metabolic profilingLearning theories reveal loss of pancreatic electrical connectivity in diabetes as an adaptive responseExpedited approaches to whole cell electron tomography and organelle mark-up in situ in high-pressure frozen pancreatic isletsThe chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution.Gap junction coupling and calcium waves in the pancreatic isletRapid and inexpensive fabrication of polymeric microfluidic devices via toner transfer maskingDemonstration of Interposed Modular Hydrogel Sheet for Multicellular Analysis in a Microfluidic Assembly Platform.Culturing pancreatic islets in microfluidic flow enhances morphology of the associated endothelial cells.Interleukin-6 amplifies glucagon secretion: coordinated control via the brain and pancreas.Somatostatin and insulin mediate glucose-inhibited glucagon secretion in the pancreatic α-cell by lowering cAMPNovel stable isotope analyses demonstrate significant rates of glucose cycling in mouse pancreatic islets.Islet preconditioning via multimodal microfluidic modulation of intermittent hypoxia.Resealable, optically accessible, PDMS-free fluidic platform for ex vivo interrogation of pancreatic islets.Dual microfluidic perifusion networks for concurrent islet perifusion and optical imaging.Microfluidic device for multimodal characterization of pancreatic isletsMicrofluidic perfusion system for automated delivery of temporal gradients to islets of Langerhans.Application of microfluidic technology to pancreatic islet research: first decade of endeavor.Brain slice on a chip: opportunities and challenges of applying microfluidic technology to intact tissues.Minireview: intraislet regulation of insulin secretion in humans.Cellular communication and heterogeneity in pancreatic islet insulin secretion dynamics.Microfluidic perfusion systems for secretion fingerprint analysis of pancreatic islets: applications, challenges and opportunities.Progress and challenges of the bioartificial pancreas.Highly efficient adenoviral transduction of pancreatic islets using a microfluidic device.A microfluidic platform for probing small artery structure and function.Implication of mitochondrial cytoprotection in human islet isolation and transplantation.Intrinsic islet heterogeneity and gap junction coupling determine spatiotemporal Ca²⁺ wave dynamicsMicrofluidic platform for assessing pancreatic islet functionality through dielectric spectroscopy.A mathematical model of β-cells in an islet of Langerhans sensing a glucose gradient.A subcellular model of glucose-stimulated pancreatic insulin secretion.Microfluidic perifusion and imaging device for multi-parametric islet function assessment.Cellular modeling: insight into oral minimal models of insulin secretion.Wave-block due to a threshold gradient underlies limited coordination in pancreatic islets.A stochastic mathematical model to study the autoimmune progression towards type 1 diabetes.Microfluidics study of intracellular calcium response to mechanical stimulation on single suspension cells.A microfluidic device designed to induce media flow throughout pancreatic islets while limiting shear-induced damage.Microphysiological Analysis Platform of Pancreatic Islet β-Cell Spheroids.Gap-junction coupling and ATP-sensitive potassium channels in human β-cell clusters: Effects on emergent dynamics.
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P2860
Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic islets
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 18 August 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Microfluidic glucose stimulati ...... illations in pancreatic islets
@en
Microfluidic glucose stimulati ...... llations in pancreatic islets.
@nl
type
label
Microfluidic glucose stimulati ...... illations in pancreatic islets
@en
Microfluidic glucose stimulati ...... llations in pancreatic islets.
@nl
prefLabel
Microfluidic glucose stimulati ...... illations in pancreatic islets
@en
Microfluidic glucose stimulati ...... llations in pancreatic islets.
@nl
P2093
P2860
P921
P356
P1476
Microfluidic glucose stimulati ...... illations in pancreatic islets
@en
P2093
David W Piston
Glenn M Walker
Jonathan V Rocheleau
Owen P McGuinness
W Steven Head
P2860
P304
12899-12903
P356
10.1073/PNAS.0405149101
P407
P577
2004-08-18T00:00:00Z