Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states.

Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states.

Item
http://www.wikidata.org/entity/Q37512931
Asymmetry of the endogenous opioid system in the human anterior cingulate: a putative molecular basis for lateralization of emotions and pain.Impaired periamygdaloid-cortex prodynorphin is characteristic of opiate addiction and depression.PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort.Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent.κ-Opioid receptors in the central amygdala regulate ethanol actions at presynaptic GABAergic sites.A variant on the kappa opioid receptor gene (OPRK1) is associated with stress response and related drug craving, limbic brain activation and cocaine relapse risk.Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment.Kappa-opioid receptors differentially regulate low and high levels of ethanol intake in female mice.Emerging Role of Epigenetic Mechanisms in Alcohol Addiction.Role of the Dynorphin/Kappa Opioid Receptor System in the Motivational Effects of Ethanol.Opiate Drugs with Abuse Liability Hijack the Endogenous Opioid System to Disrupt Neuronal and Glial Maturation in the Central Nervous System.
P2860

Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states.

Item
http://www.wikidata.org/entity/Q37512931
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 29 October 2012
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Association of the PDYN gene w ...... in negative emotional states.
@en
Association of the PDYN gene w ...... in negative emotional states.
@nl
type
label
Association of the PDYN gene w ...... in negative emotional states.
@en
Association of the PDYN gene w ...... in negative emotional states.
@nl
prefLabel
Association of the PDYN gene w ...... in negative emotional states.
@en
Association of the PDYN gene w ...... in negative emotional states.
@nl
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P1476
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P478
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P577
P698
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P1433
P1476
Association of the PDYN gene w ...... in negative emotional states.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932