Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.
about
A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency.A genome-wide CRISPR screen reconciles the role of N-linked glycosylation in galectin-3 transport to the cell surface.Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy.Accumulation of autophagosomes confers cytotoxicity.Insights into links between autophagy and the ubiquitin system from the structure of LC3B bound to the LIR motif from the E3 ligase NEDD4.Structural and functional analysis of the GABARAP interaction motif (GIM).Molecular definitions of autophagy and related processes.Genetic control of autophagy underlies pathogenesis of inflammatory bowel disease.The coordination of membrane fission and fusion at the end of autophagosome maturation.No ATG8s, no problem? How LC3/GABARAP proteins contribute to autophagy.Assays to Monitor Autophagy Progression in Cell Cultures.Clinical Applications of Autophagy Proteins in Cancer: From Potential Targets to Biomarkers.Monitoring and Measuring Autophagy.Inverted recruitment of autophagy proteins to the Plasmodium berghei parasitophorous vacuole membrane.iLIR@viral: a web resource for LIR motif-containing proteins in viruses.Atg4 plays an important role in efficient expansion of autophagic isolation membranes by cleaving lipidated Atg8 in Saccharomyces cerevisiae.GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF-7 breast cancer cells.NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy.PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease.Innate Immunity to Intracellular Pathogens: Balancing Microbial Elimination and Inflammation.Systematic analysis of human cells lacking ATG8 proteins uncovers roles for GABARAPs and the CCZ1/MON1 regulator C18orf8/RMC1 in macro and selective autophagic flux.Traditional Chinese medicine Ka-Sai-Ping suppresses the growths of gastric cancers via induction of autophagy.Oxidation of Atg3 and Atg7 mediates inhibition of autophagy.Evolution of tools and methods for monitoring autophagic flux in mammalian cells.CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis.Regulation of selective autophagy: the p62/SQSTM1 paradigm.Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion.Dysregulation of autophagy as a common mechanism in lysosomal storage diseases.Mammalian mitophagy - from in vitro molecules to in vivo models.Development of LC3/GABARAP sensors containing a LIR and a hydrophobic domain to monitor autophagy.FKBP8 recruits LC3A to mediate Parkin-independent mitophagy.The IAP family member BRUCE regulates autophagosome-lysosome fusion.Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases.Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion.Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence.eIF5A is required for autophagy by mediating ATG3 translationStarvation induces rapid degradation of selective autophagy receptors by endosomal microautophagyAutophagy-independent induction of LC3B through oxidative stress reveals its non-canonical role in anoikis of ovarian cancer cells
P2860
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P2860
Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Atg8 family LC3/GABARAP protei ...... rkin mitophagy and starvation.
@en
Atg8 family LC3/GABARAP protei ...... rkin mitophagy and starvation.
@nl
type
label
Atg8 family LC3/GABARAP protei ...... rkin mitophagy and starvation.
@en
Atg8 family LC3/GABARAP protei ...... rkin mitophagy and starvation.
@nl
prefLabel
Atg8 family LC3/GABARAP protei ...... rkin mitophagy and starvation.
@en
Atg8 family LC3/GABARAP protei ...... rkin mitophagy and starvation.
@nl
P2860
P50
P356
P1476
Atg8 family LC3/GABARAP protei ...... arkin mitophagy and starvation
@en
P2093
Joanne Usher
P2860
P304
P356
10.1083/JCB.201607039
P407
P577
2016-11-18T00:00:00Z