Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing. - Wikidata - awgldk - TriplyDB

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

http://www.wikidata.org/entity/Q37518627

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Solution Structure and DNA-binding Properties of the Winged Helix Domain of the Meiotic Recombination HOP2 Protein Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair Connecting by breaking and repairing: mechanisms of DNA strand exchange in meiotic recombination Entamoeba histolytica Dmc1 Catalyzes Homologous DNA Pairing and Strand Exchange That Is Stimulated by Calcium and Hop2-Mnd1 The third exon of the budding yeast meiotic recombination gene HOP2 is required for calcium-dependent and recombinase Dmc1-specific stimulation of homologous strand assimilation.HOP2-MND1 modulates RAD51 binding to nucleotides and DNA.DNA strand exchange and RecA homologs in meiosis Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination.Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homologous DNA repair and XX ovarian dysgenesis Identification of the meiotic toolkit in diatoms and exploration of meiosis-specific SPO11 and RAD51 homologs in the sexual species Pseudo-nitzschia multistriata and Seminavis robusta.Functional Relationship of ATP Hydrolysis, Presynaptic Filament Stability, and Homologous DNA Pairing Activity of the Human Meiotic Recombinase DMC1.Tolerance of DNA Mismatches in Dmc1 Recombinase-mediated DNA Strand Exchange.GT198 (PSMC3IP) germline variants in early-onset breast cancer patients from hereditary breast and ovarian cancer families.Weak protein-ligand interactions studied by small-angle X-ray scattering.Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors Wing 1 of protein HOP2 is as important as helix 3 in DNA binding by MD simulation.BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.Sufficient amounts of functional HOP2/MND1 complex promote interhomolog DNA repair but are dispensable for intersister DNA repair during meiosis in Arabidopsis.

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Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

http://www.wikidata.org/entity/Q37518627

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 22 October 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

@en

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

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type

label

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

@en

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

@nl

prefLabel

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

@en

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

@nl

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Nucleic Acids Research

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Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.

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Dorina Saro

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Gareth J Williams

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Hong-Wei Wang

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Lucy Lu

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Patrick Sung

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R Daniel Camerini-Otero

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Robert P Rambo

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Roberto J Pezza

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Youngho Kwon

http://www.w3.org/2001/XMLSchema#string

Yuanyuan Xu

http://www.w3.org/2001/XMLSchema#string

P2860

Homologous Pairing and Strand Exchange in Genetic Recombination

Clarifying the mechanics of DNA strand exchange in meiotic recombination

Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing

Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing

Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding

Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing.

Meiotic chromosomes: it takes two to tango.

Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeast.

DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression.

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10.1093/NAR/GKT924

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