The fine specificity, but not the invasion inhibitory activity, of 19-kilodalton merozoite surface protein 1-specific antibodies is associated with resistance to malarial parasitemia in a cross-sectional survey in The Gambia.
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Histidine affinity tags affect MSP1(42) structural stability and immunodominance in mice.Acquisition of invasion-inhibitory antibodies specific for the 19-kDa fragment of merozoite surface protein 1 in a transmigrant population requires multiple infections.Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya.Construction of transgenic Plasmodium berghei as a model for evaluation of blood-stage vaccine candidate of Plasmodium falciparum chimeric protein 2.9.The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malariaGrowth-inhibitory antibodies are not necessary for protective immunity to malaria infection.In vitro growth-inhibitory activity and malaria risk in a cohort study in maliPlasmodium falciparum merozoite surface protein 1 (MSP-1)-MSP-3 chimeric protein: immunogenicity determined with human-compatible adjuvants and induction of protective immune response.Development of fluorescent Plasmodium falciparum for in vitro growth inhibition assaysQuantifying the importance of MSP1-19 as a target of growth-inhibitory and protective antibodies against Plasmodium falciparum in humans.Fine specificity of anti-MSP119 antibodies and multiplicity of Plasmodium falciparum merozoite surface protein 1 types in individuals in Nigeria with sub-microscopic infection.Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodesImmunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunizedDetecting Foci of Malaria Transmission with School Surveys: A Pilot Study in the Gambia.Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children.Antibodies to Plasmodium falciparum erythrocyte-binding antigen-175 are associated with protection from clinical malaria.Revisiting the effect of acute P. falciparum malaria on Epstein-Barr virus: host balance in the setting of reduced malaria endemicity.Plasmodium falciparum 19-kilodalton merozoite surface protein 1 (MSP1)-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion, and intracellular parasite development.Malaria invasion ligand RH5 and its prime candidacy in blood-stage malaria vaccine designAntibodies elicited in adults by a primary Plasmodium falciparum blood-stage infection recognize different epitopes compared with immune individualsPlasmodium falciparum line-dependent association of in vitro growth-inhibitory activity and risk of malaria.Serology describes a profile of declining malaria transmission in Farafenni, The GambiaCan growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy?Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malariaDiversity covering AMA1-MSP119 fusion proteins as malaria vaccines.Cohort study of the association of antibody levels to AMA1, MSP119, MSP3 and GLURP with protection from clinical malaria in Ghanaian children.Identification of residues in the Cmu4 domain of polymeric IgM essential for interaction with Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1).Plasmodium falciparum merozoite surface antigen, PfRH5, elicits detectable levels of invasion-inhibiting antibodies in humans.Inhibitory antibodies specific for the 19-kilodalton fragment of merozoite surface protein 1 do not correlate with delayed appearance of infection with Plasmodium falciparum in semi-immune individuals in VietnamHow might infant and paediatric immune responses influence malaria vaccine efficacy?What you see is not what you get: implications of the brevity of antibody responses to malaria antigens and transmission heterogeneity in longitudinal studies of malaria immunity.Cellular responses to modified Plasmodium falciparum MSP119 antigens in individuals previously exposed to natural malaria infection.Comparison of surveillance methods applied to a situation of low malaria prevalence at rural sites in The Gambia and Guinea Bissau.The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria.Diversity and population structure of Plasmodium falciparum in Thailand based on the spatial and temporal haplotype patterns of the C-terminal 19-kDa domain of merozoite surface protein-1The generation and evaluation of two panels of epitope-matched mouse IgG1, IgG2a, IgG2b and IgG3 antibodies specific for Plasmodium falciparum and Plasmodium yoelii merozoite surface protein 1-19 (MSP1(19)).Variation in the immune responses against Plasmodium falciparum merozoite surface protein-1 and apical membrane antigen-1 in children residing in the different epidemiological strata of malaria in Cameroon.
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The fine specificity, but not the invasion inhibitory activity, of 19-kilodalton merozoite surface protein 1-specific antibodies is associated with resistance to malarial parasitemia in a cross-sectional survey in The Gambia.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on October 2004
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The fine specificity, but not ...... ectional survey in The Gambia.
@en
The fine specificity, but not ...... ectional survey in The Gambia.
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type
label
The fine specificity, but not ...... ectional survey in The Gambia.
@en
The fine specificity, but not ...... ectional survey in The Gambia.
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prefLabel
The fine specificity, but not ...... ectional survey in The Gambia.
@en
The fine specificity, but not ...... ectional survey in The Gambia.
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The fine specificity, but not ...... ectional survey in The Gambia.
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Chairat Uthaipibull
Patrick H Corran
Rebecca A O'Donnell
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10.1128/IAI.72.10.6185-6189.2004
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2004-10-01T00:00:00Z