The role of OX40-mediated co-stimulation in T-cell activation and survival. - Wikidata - awgldk - TriplyDB

The role of OX40-mediated co-stimulation in T-cell activation and survival.

The role of OX40-mediated co-stimulation in T-cell activation and survival.

http://www.wikidata.org/entity/Q37524064

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The Role of Lymphatic Niches in T Cell Differentiation Balancing Immune Protection and Immune Pathology by CD8(+) T-Cell Responses to Influenza Infection Molecular mechanisms of T cell co-stimulation and co-inhibition The role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosis Role of immune escape mechanisms in Hodgkin's lymphoma development and progression: a whole new world with therapeutic implications Dual anti-OX40/IL-2 therapy augments tumor immunotherapy via IL-2R-mediated regulation of OX40 expression Activation of OX40 augments Th17 cytokine expression and antigen-specific uveitis.The tumor-immune microenvironment and response to radiation therapy HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma.OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.Small-molecule modulators of the OX40-OX40 ligand co-stimulatory protein-protein interaction Roscovitine suppresses CD4+ T cells and T cell-mediated experimental uveitis.PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancer.Activation of OX40 prolongs and exacerbates autoimmune experimental uveitis Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype Characterization of tumor infiltrating lymphocytes in paired primary and metastatic renal cell carcinoma specimens.Combination OX40 agonism/CTLA-4 blockade with HER2 vaccination reverses T-cell anergy and promotes survival in tumor-bearing mice.Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival A novel differentiation pathway from CD4⁺ T cells to CD4⁻ T cells for maintaining immune system homeostasis Host and microbial factors in regulation of T cells in the intestine.New insights into the role of the immune microenvironment in breast carcinoma.CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo.Antibodies targeting human OX40 expand effector T cells and block inducible and natural regulatory T cell function.Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2V617F allelic burden.The Suppressed Induction of Human Mature Cytotoxic T Lymphocytes Caused by Asbestos Is Not due to Interleukin-2 Insufficiency RNA Sequencing Analysis Reveals Interactions between Breast Cancer or Melanoma Cells and the Tissue Microenvironment during Brain Metastasis.Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice.OX40 signaling is involved in the autoactivation of CD4+CD28- T cells and contributes to the pathogenesis of autoimmune arthritis.Chimeric antigen receptor-engineered T cells for immunotherapy of cancer.Signaling through OX40 enhances antitumor immunity.Deciphering the genetic background of systemic sclerosis.Genetics of systemic sclerosis: an update.Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells.The confluence of radiotherapy and immunotherapy.Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse.Feline immunodeficiency virus latency.OX40 Agonists and Combination Immunotherapy: Putting the Pedal to the Metal.TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity.How do I steer this thing? Using dendritic cell targeted vaccination to more effectively guide the antitumor immune response with combination immunotherapy.

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The role of OX40-mediated co-stimulation in T-cell activation and survival.

http://www.wikidata.org/entity/Q37524064

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on January 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

The role of OX40-mediated co-stimulation in T-cell activation and survival.

@en

The role of OX40-mediated co-stimulation in T-cell activation and survival.

@nl

type

label

The role of OX40-mediated co-stimulation in T-cell activation and survival.

@en

The role of OX40-mediated co-stimulation in T-cell activation and survival.

@nl

prefLabel

The role of OX40-mediated co-stimulation in T-cell activation and survival.

@en

The role of OX40-mediated co-stimulation in T-cell activation and survival.

@nl

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CRITREVIMMUNOL.V29.I3.10

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Critical Reviews in Immunology

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The role of OX40-mediated co-stimulation in T-cell activation and survival.

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Andrew D Weinberg

http://www.w3.org/2001/XMLSchema#string

Carl E Ruby

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William L Redmond

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P2860

4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB

Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

The costimulation-regulated duration of PKB activation controls T cell longevity

TNF/TNFR family members in costimulation of T cell responses

Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion

Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2- and TRAF5-mediated NF-kappaB activation

OX40/OX40L interaction induces the expression of CXCR5 and contributes to chronic colitis induced by dextran sulfate sodium in mice

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187-201

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scholarly article

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10.1615/CRITREVIMMUNOL.V29.I3.10

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3

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29

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2009-01-01T00:00:00Z

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19538134

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3180959

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