The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy.
about
The Origin and Activities of IgA1-Containing Immune Complexes in IgA NephropathyInterleukin-6 Signaling Pathway and Its Role in Kidney Disease: An UpdateThe combined role of galactose-deficient IgA1 and streptococcal IgA-binding M Protein in inducing IL-6 and C3 secretion from human mesangial cells: implications for IgA nephropathy.Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis.C5a Induces the Synthesis of IL-6 and TNF-α in Rat Glomerular Mesangial Cells through MAPK Signaling Pathways.New Insights into the Pathogenesis of IgA Nephropathy.CCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy.β-Arrestins Negatively Regulate the Toll Pathway in Shrimp by Preventing Dorsal Translocation and Inhibiting Dorsal Transcriptional ActivityGlomerular and tubular C4d depositions in IgA nephropathy: relations with histopathology and with albuminuria.Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2)Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.Protein Array-Based Detection of Proteins in Kidney Tissues from Patients with Membranous NephropathySublytic C5b-9 triggers glomerular mesangial cell apoptosis via XAF1 gene activation mediated by p300-dependent IRF-1 acetylation.IgG-Fc N-glycosylation at Asn297 and IgA O-glycosylation in the hinge region in health and disease.Lessons from rodent models in celiac disease.Paradigm shift in activity assessment of IgA nephropathy - optimizing the next generation of diagnostic and therapeutic maneuvers via glycan targeting.Role of IgA receptors in the pathogenesis of IgA nephropathy.The mTOR/p70S6K1 signaling pathway in renal fibrosis of children with immunoglobulin A nephropathy.Network Module-Based Model in the Differential Expression Analysis for RNA-seq.Immunoglobulin A nephropathy: a pathophysiology view.IgA nephropathy enigma.Combined C4d and CD3 immunostaining predicts immunoglobulin (Ig)A nephropathy progression.Abnormal apical-to-basal transport of dietary ovalbumin by secretory IgA stimulates a mucosal Th1 response.Sublytic C5b-9 triggers glomerular mesangial cell apoptosis in rat Thy-1 nephritis via Gadd45 activation mediated by Egr-1 and p300-dependent ATF3 acetylation.Role of MAPK signal pathways in differentiation process of M2 macrophages induced by high-ambient glucose and TGF-β1.New insights into the pathogenesis of IgA nephropathy
P2860
Q26752555-B2002696-1304-4D79-93C0-3AA026176211Q33586501-454F681F-4A8B-4553-8593-45740B4E223DQ33787385-C21D0702-A5D1-42C0-9A16-A6249677CC82Q35790612-C42D3369-5C8A-42E0-8BB6-DE466647C914Q36119713-297F4B5E-580D-4882-98C6-9FAE9CE5D7F9Q36267833-0EAF44D7-E122-4D2D-9024-1FF6F422CEF8Q36383807-3C431B53-1E65-4524-9537-684E85C82BFCQ36755034-02E77CEF-FFA6-4333-A2C1-6221F9CADB05Q36800330-26F55E9A-B79A-4A0A-9EC3-72FB9EC0B508Q36947844-B4F02C96-5022-45FB-AFD6-2F490B1A5C78Q37596411-04436AAA-0401-4060-AE08-8C13A5CFA364Q37699835-CECCCDCA-46DE-40A4-96CB-DAE08611507DQ37726137-8AF880C4-8450-45A8-AC4F-500823096A2AQ38115691-7B623487-CE9E-4A5F-9562-552C59E05D2DQ38263650-4455E3B7-A8D5-420A-9B7D-82AFC52F94FDQ38325438-36892843-C962-40EF-9CDF-67AB22C1EC12Q38634418-2F554279-49FA-4BD7-A2D2-F665A81ABAF8Q38661458-930D432F-DE80-402B-8469-C29A958C12E9Q38838346-FBDAE264-17B5-4A9E-BB64-9A2C417199B2Q38879517-B4C207CB-03D5-4AF2-8714-F6085BC7A603Q38904812-D8085210-32ED-4C54-A637-4B46492D0A01Q41722238-F6073647-4CD7-412D-85B8-B085F5D727F9Q42441197-32A3E582-C7D8-40DC-99B1-6E5D44C976EDQ52868803-B1FA12E6-A919-41A8-B86B-CDCCA77B0CFBQ54323819-C6AFF629-1795-484A-8868-27FB00487F2DQ58006979-04FFBFC5-E11E-4827-B611-7A311C8D65D0
P2860
The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 September 2012
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The IgA1 immune complex-mediat ...... lar damage in IgA nephropathy.
@en
The IgA1 immune complex-mediat ...... lar damage in IgA nephropathy.
@nl
type
label
The IgA1 immune complex-mediat ...... lar damage in IgA nephropathy.
@en
The IgA1 immune complex-mediat ...... lar damage in IgA nephropathy.
@nl
prefLabel
The IgA1 immune complex-mediat ...... lar damage in IgA nephropathy.
@en
The IgA1 immune complex-mediat ...... lar damage in IgA nephropathy.
@nl
P2093
P2860
P356
P1433
P1476
The IgA1 immune complex-mediat ...... lar damage in IgA nephropathy.
@en
P2093
Bruce A Julian
Emilie Tissandié
Etienne Paubelle
Francine Walker
François Vrtovsnik
Houda Tamouza
Ivan C Moura
Jonathan M Chemouny
Laureline Berthelot
P2860
P2888
P304
P356
10.1038/KI.2012.192
P407
P577
2012-09-05T00:00:00Z
P5875
P6179
1041997084