Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
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Gram-positive and gram-negative bacterial toxins in sepsis: a brief reviewBacterial Toxins as Pathogen Weapons Against PhagocytesCrossing of the epithelial barriers by Bacillus anthracis: the Known and the UnknownAnthrax prophylaxis: recent advances and future directionsAnthrax lethal and edema toxins in anthrax pathogenesisBacillus anthracis factors for phagosomal escapeBacillus anthracis edema factor substrate specificity: evidence for new modes of actionCytoskeleton as an emerging target of anthrax toxinsCellular and physiological effects of anthrax exotoxin and its relevance to disease.The potential contributions of lethal and edema toxins to the pathogenesis of anthrax associated shockQuantitative models of the dose-response and time course of inhalational anthrax in humansAntidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chainAlternative pre-approved and novel therapies for the treatment of anthraxThe effects of anthrax lethal toxin on host barrier functionAnthrax lethal toxin disrupts intestinal barrier function and causes systemic infections with enteric bacteriaNoninvasive imaging technologies reveal edema toxin as a key virulence factor in anthraxMolecular motions as a drug target: mechanistic simulations of anthrax toxin edema factor function led to the discovery of novel allosteric inhibitors.Bacillus anthracis cell wall peptidoglycan but not lethal or edema toxins produces changes consistent with disseminated intravascular coagulation in a rat model.Contributions of edema factor and protective antigen to the induction of protective immunity by Bacillus anthracis edema toxin as an intranasal adjuvantInflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment.Sublethal doses of anthrax lethal toxin on the suppression of macrophage phagocytosis.Exposure to Bacillus anthracis capsule results in suppression of human monocyte-derived dendritic cellsNew developments in vaccines, inhibitors of anthrax toxins, and antibiotic therapeutics for Bacillus anthracis.Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins.Both lethal and edema toxins of Bacillus anthracis disrupt the human dendritic cell chemokine network.Anthrax toxin targeting of myeloid cells through the CMG2 receptor is essential for establishment of Bacillus anthracis infections in mice.New insights into gastrointestinal anthrax infection.Consequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.The poly-γ-D-glutamic acid capsule of Bacillus anthracis enhances lethal toxin activity.Anthrax edema toxin impairs clearance in mice.Micropatterned macrophage analysis reveals global cytoskeleton constraints induced by Bacillus anthracis edema toxin.Anthrax and the inflammasomeNitric oxide as a regulator of B. anthracis pathogenicity.From structure to solutions: the role of basic research in developing anthrax countermeasures: Microbiology Graduate Program Seminar: Anthrax toxin.Differential contribution of Bacillus anthracis toxins to pathogenicity in two animal modelsGlobal metabolomic analysis of a mammalian host infected with Bacillus anthracis.The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesisIn vivo dynamics of active edema and lethal factors during anthrax.Characterization of the native form of anthrax lethal factor for use in the toxin neutralization assay.Small-molecule inhibitors of lethal factor protease activity protect against anthrax infection.
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Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
@en
Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
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type
label
Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
@en
Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
@nl
prefLabel
Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
@en
Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
@nl
P2093
P1476
Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
@en
P2093
Anne Quesnel-Hellmann
Cosima T Baldari
Jean-Nicolas Tournier
Silvia Rossi Paccani
P304
P356
10.1016/J.MAM.2009.06.002
P577
2009-06-26T00:00:00Z