Age, gender, and cancer but not neurodegenerative and cardiovascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan.
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Diametrical diseases reflect evolutionary-genetic tradeoffs: Evidence from psychiatry, neurology, rheumatology, oncology and immunologyHow Genes Modulate Patterns of Aging-Related Changes on the Way to 100: Biodemographic Models and Methods in Genetic Analyses of Longitudinal DataGenome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairmentVariants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan.No association between Apoε4 alleles, HIV infection, age, neuropsychological outcome, or death.Association of the apolipoprotein E 2 allele with concurrent occurrence of endometrial hyperplasia and endometrial carcinoma.Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study.Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and MortalityThe Distribution of Apolipoprotein E Gene Polymorphism and Apolipoprotein E Levels among Coronary Artery Patients Compared to ControlsPleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.Explicating heterogeneity of complex traits has strong potential for improving GWAS efficiency.The role of apolipoprotein E episilon (ε)-4 allele on outcome following traumatic brain injury: A systematic review.Apolipoprotein E4 is associated with improved cognitive function in Amazonian forager-horticulturalists with a high parasite burden.Alzheimer's disease genetic risk variants beyond APOE ε4 predict mortality.Protective role of the apolipoprotein E2 allele in age-related disease traits and survival: evidence from the Long Life Family Study.Identification of polymorphisms in cancer patients that differentially affect survival with age.Are the effects ofAPOEϵ4 on cognitive function in nonclinical populations age- and gender-dependent?Age stratification corrects bias in estimated hazard of genotype for Alzheimer's disease
P2860
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P2860
Age, gender, and cancer but not neurodegenerative and cardiovascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 30 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Age, gender, and cancer but no ...... protein E4 allele on lifespan.
@en
Age, gender, and cancer but no ...... protein E4 allele on lifespan.
@nl
type
label
Age, gender, and cancer but no ...... protein E4 allele on lifespan.
@en
Age, gender, and cancer but no ...... protein E4 allele on lifespan.
@nl
prefLabel
Age, gender, and cancer but no ...... protein E4 allele on lifespan.
@en
Age, gender, and cancer but no ...... protein E4 allele on lifespan.
@nl
P2093
P2860
P1433
P1476
Age, gender, and cancer but no ...... protein E4 allele on lifespan.
@en
P2093
Alexander M Kulminski
Anatoli I Yashin
Eric Stallard
Irina Culminskaya
Konstantin G Arbeev
Liubov Arbeeva
Nicole Schupf
Svetlana V Ukraintseva
P2860
P304
P356
10.1371/JOURNAL.PGEN.1004141
P577
2014-01-30T00:00:00Z