GCN5-like protein 1 (GCN5L1) controls mitochondrial content through coordinated regulation of mitochondrial biogenesis and mitophagy
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Defining the orphan functions of lysine acetyltransferasesMolecular mechanisms of mitochondrial autophagy/mitophagy in the heartRegulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stressBiogenesis of lysosome-related organelles complex-1 subunit 1 (BLOS1) interacts with sorting nexin 2 and the endosomal sorting complex required for transport-I (ESCRT-I) component TSG101 to mediate the sorting of epidermal growth factor receptor intA time to reap, a time to sow: mitophagy and biogenesis in cardiac pathophysiologySIRT3 mediates multi-tissue coupling for metabolic fuel switchingTransition metals activate TFEB in overexpressing cellsFasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects.The regulation of autophagy during exercise in skeletal muscleAging and Autophagy in the HeartRegulation of autophagy and mitophagy by nutrient availability and acetylation.Protein acetylation as a means to regulate protein function in tune with metabolic state.Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.Acetylation and succinylation contribute to maturational alterations in energy metabolism in the newborn heart.Mitochondrial autophagy in cardiomyopathy.Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.Transcription factor EB: from master coordinator of lysosomal pathways to candidate therapeutic target in degenerative storage diseases.Mitochondrial biogenesis and clearance: a balancing act.PGC-1α buffers ROS-mediated removal of mitochondria during myogenesis.The TDH-GCN5L1-Fbxo15-KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells.GCN5L1 modulates cross-talk between mitochondria and cell signaling to regulate FoxO1 stability and gluconeogenesis.PGC-1α modulates denervation-induced mitophagy in skeletal muscle.Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats.Mitophagy as a Protective Mechanism against Myocardial Stress.The Mitochondrial Basis of Aging and Age-Related Disorders.Exercise induces TFEB expression and activity in skeletal muscle in a PGC-1α-dependent manner.Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish.Protein coingestion with alcohol following strenuous exercise attenuates alcohol-induced intramyocellular apoptosis and inhibition of autophagy.GCN5L1/BLOS1 Links Acetylation, Organelle Remodeling, and Metabolism.α-Lipoic acid promotes α-tubulin hyperacetylation and blocks the turnover of mitochondria through mitophagy.Mitochondrial protein acetylation mediates nutrient sensing of mitochondrial protein synthesis and mitonuclear protein balance.Acetylation contributes to hypertrophy-caused maturational delay of cardiac energy metabolism.Adropin regulates pyruvate dehydrogenase in cardiac cells via a novel GPCR-MAPK-PDK4 signaling pathway.Emerging roles and regulation of MiT/TFE transcriptional factors.The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA
P2860
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P2860
GCN5-like protein 1 (GCN5L1) controls mitochondrial content through coordinated regulation of mitochondrial biogenesis and mitophagy
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 19 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
GCN5-like protein 1 (GCN5L1) c ...... drial biogenesis and mitophagy
@en
GCN5-like protein 1
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type
label
GCN5-like protein 1 (GCN5L1) c ...... drial biogenesis and mitophagy
@en
GCN5-like protein 1
@nl
prefLabel
GCN5-like protein 1 (GCN5L1) c ...... drial biogenesis and mitophagy
@en
GCN5-like protein 1
@nl
P2093
P2860
P356
P1476
GCN5-like protein 1 (GCN5L1) c ...... drial biogenesis and mitophagy
@en
P2093
Bradley R Webster
Carmen K Chan
Iain Scott
Joshua U Okonkwo
Michael N Sack
P2860
P304
P356
10.1074/JBC.M113.521641
P407
P577
2013-12-19T00:00:00Z