about
Dietary, metabolic, and potentially environmental modulation of the lysine acetylation machineryStructure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)Targeting cancer using KAT inhibitors to mimic lethal knockoutsHistone acetyltransferases: challenges in targeting bi-substrate enzymesThe Impact of External Factors on the Epigenome: In Utero and over LifetimeA dynamic interface between ubiquitylation and cAMP signalingDesign of small molecule epigenetic modulatorsBeyond the genome: epigenetic mechanisms in lung remodelingHDAC activity is required during Xenopus tail regenerationDimeric structure of p300/CBP associated factorFate determination in mesenchymal stem cells: a perspective from histone-modifying enzymesHistone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyAnacardic acids from cashew nuts ameliorate lung damage induced by exposure to diesel exhaust particles in miceAuto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survivalSalicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activityHistone acetyltransferase inhibitors block neuroblastoma cell growth in vivoThe histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases.Towards new approaches to disorders of fear and anxiety.Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitorA combination of p300 and Braf expression in the diagnosis and prognosis of melanomaApplication of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthaseEpigenetics meets endocrinology.Histone acetyltransferases are crucial regulators in NF-κB mediated inflammation.Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellumSmall molecule inhibitors of histone acetyltransferases as epigenetic tools and drug candidates.Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction.Acetylation-mediated suppression of transcription-independent memory: bidirectional modulation of memory by acetylationPotential biological applications of bio-based anacardic acids and their derivatives.Use of epigenetic drugs in disease: an overview.Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents.Three-dimensional collagen I promotes gemcitabine resistance in vitro in pancreatic cancer cells through HMGA2-dependent histone acetyltransferase expression.Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome.Interpreting clinical assays for histone deacetylase inhibitors.Heparanase-mediated loss of nuclear syndecan-1 enhances histone acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotypeHigh throughput screening identifies modulators of histone deacetylase inhibitorsGcn5 Modulates the Cellular Response to Oxidative Stress and Histone Deacetylase Inhibition.Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair.The stability of histone acetyltransferase general control non-derepressible (Gcn) 5 is regulated by Cullin4-RING E3 ubiquitin ligase.Altering cancer transcriptomes using epigenomic inhibitorsElevated H3K18 acetylation in airway epithelial cells of asthmatic subjects.
P2860
Q21296850-C619149F-C223-4B76-8E8D-826191362CFFQ26314426-F62A0C23-30F1-482A-8E65-6513CFD1D4DCQ26741346-57B36FFC-4AED-46EF-989F-2B2BA20E05FDQ26745642-75238AA0-0D94-4332-AFCC-64C1EC022171Q26746703-36D842CE-BF20-4E7B-B4B0-7D9FF72F79D1Q26782981-340378B1-773E-4720-9660-1AAC0B386D54Q26850027-A7388F58-C4B7-476B-B9D6-69E45382C523Q27021767-B51BDD1F-75C9-4AA7-B1E7-219E494B3B57Q27316244-00F21EDF-AC2A-4D44-B8F9-75A74C1AB20FQ27681322-ECE7DA43-4F0A-48CA-988A-ACFCD0E70256Q27692571-35580315-3AC2-45AA-8534-269E54DF2222Q28082536-3588481C-7B89-4E4B-9507-F2DCE2A6E282Q28395758-53FF32D1-2C87-420C-9D15-C585E31A9435Q28577251-7618D27C-E953-415A-A8D9-D75F25F76B73Q28831354-CF7A4620-9F6D-4287-A36F-0AFA7D136848Q30316789-79E15FF6-7417-4DEF-B382-350A724C57C9Q30383560-F200CEE7-861A-4464-87BA-C71026D9AF3CQ30437494-385E5E61-6E01-4F72-800D-61B178EB8D2CQ33599508-ACFC149D-9DF8-4B71-AA43-438FD3E381CBQ33733125-C958EA28-EEAB-424C-A1FF-91B71F59578EQ33745848-3341B609-A55B-4FFA-84AD-4426600EE829Q33810295-C31F9AC4-98FD-4BC0-877C-DBD10F5C8A3CQ33866592-34D43F64-36A1-4395-8C8D-9E1A7603CDD1Q33927405-39CA9C89-DBFC-46A9-ACB1-7515452D8EE4Q34123380-258C7A30-C9B6-44CB-A120-BB4D88DD7699Q34236804-CA433E74-EA05-497F-937B-19BA2905679EQ34428163-D8FC7027-768C-4887-8768-57F1B5F30B55Q34472671-93704F13-8D65-4EE4-BDD4-C87B30FC9A96Q34607095-28A9146B-D368-495B-93A6-E3144B3F1A55Q34692024-E25BEF62-1806-4780-BDDE-0A0699DA1AB3Q34734222-D72542BD-19F9-465A-9E22-F10B9259D466Q34831586-0258A8E1-59A5-4FFE-8226-E636C16C5DD2Q35003657-9F3D7AB9-7ED3-475F-9F68-7991D541FFE6Q35182839-C8F39C66-6CC3-431D-8437-B6ACA3B017E0Q35195856-1C807109-8064-404D-81AA-D888CAF10BB1Q35574284-CA68089E-C9EE-455E-81F9-E63C5CEA45D0Q35764015-0677D67E-E999-47D4-8B16-133605942203Q35842121-211D10BC-5A5D-4A06-A5EC-BA132DEDB0C8Q35863203-ED48D554-7E90-4332-89F4-5B5CE54B349AQ35937982-65CB5CB0-344B-4473-BBDB-A898878B286B
P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Histone acetyl transferases as emerging drug targets.
@en
Histone acetyl transferases as emerging drug targets.
@nl
type
label
Histone acetyl transferases as emerging drug targets.
@en
Histone acetyl transferases as emerging drug targets.
@nl
prefLabel
Histone acetyl transferases as emerging drug targets.
@en
Histone acetyl transferases as emerging drug targets.
@nl
P1433
P1476
Histone acetyl transferases as emerging drug targets
@en
P2093
Frank J Dekker
Hidde J Haisma
P304
P356
10.1016/J.DRUDIS.2009.06.008
P577
2009-07-02T00:00:00Z