Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice
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Inflammation in gastric cancer: Interplay of the COX-2/prostaglandin E2 and Toll-like receptor/MyD88 pathwaysTransgenic and gene knockout mice in gastric cancer researchRole of cyclooxygenase-2 in the carcinogenesis of gastrointestinal tract cancers: a review and report of personal experienceEssential role of gastric gland mucin in preventing gastric cancer in miceCanolol inhibits gastric tumors initiation and progression through COX-2/PGE2 pathway in K19-C2mE transgenic miceActivated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells.Mouse gastric tumor models with prostaglandin E2 pathway activation show similar gene expression profiles to intestinal-type human gastric cancerNon-Steroidal Anti-Inflammatory Drugs in the Carcinogenesis of the Gastrointestinal Tract.Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axisCOX-2 in liver, from regeneration to hepatocarcinogenesis: what we have learned from animal models?Wnt/β-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells.Mouse models of gastric carcinogenesis.Novel human mPGES-1 inhibitors identified through structure-based virtual screening.K-ras mutation targeted to gastric tissue progenitor cells results in chronic inflammation, an altered microenvironment, and progression to intraepithelial neoplasia.Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression.Establishment of novel in vitro mouse chief cell and SPEM cultures identifies MAL2 as a marker of metaplasia in the stomach.Mouse models of gastrointestinal tumors.Animal models of stomach carcinogenesis.Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivoMicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1.Activating enhancer-binding protein-2α induces cyclooxygenase-2 expression and promotes nasopharyngeal carcinoma growth.MMP-2 but not MMP-9 associated with COX-2 and survival in gastric cancer.The oncogenic role of JC virus T antigen in lens tumors without cell specificity of alternative splicing of its intron.Ku80 cooperates with CBP to promote COX-2 expression and tumor growth.Expression of a cyclo-oxygenase-2 transgene in murine liver causes hepatitis.Inhibition of β-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivoChemokine CXCL14 is associated with prognosis in patients with colorectal carcinoma after curative resection.Wnt signaling and gastrointestinal tumorigenesis in mouse models.Gastric stem cells and gastric cancer stem cells.Macrophages, PPARs, and Cancer.Pro-inflammatory prostaglandins and progression of colorectal cancerMouse models of gastric cancer.The invisible arm of immunity in common cancer chemoprevention agents.Inhibition of 15-hydroxyprostaglandin dehydrogenase by Helicobacter pylori in human gastric carcinogenesisThe immunological contribution of NF-κB within the tumor microenvironment: a potential protective role of zinc as an anti-tumor agent.Genetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.GCGene: a gene resource for gastric cancer with literature evidence.C/EBPβ regulates homeostatic and oncogenic gastric cell proliferationProstaglandin E(2) synthase inhibition as a therapeutic target.
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P2860
Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 March 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hyperplastic gastric tumors in ...... COX-2/mPGES-1 transgenic mice
@en
Hyperplastic gastric tumors in ...... COX-2/mPGES-1 transgenic mice.
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type
label
Hyperplastic gastric tumors in ...... COX-2/mPGES-1 transgenic mice
@en
Hyperplastic gastric tumors in ...... COX-2/mPGES-1 transgenic mice.
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prefLabel
Hyperplastic gastric tumors in ...... COX-2/mPGES-1 transgenic mice
@en
Hyperplastic gastric tumors in ...... COX-2/mPGES-1 transgenic mice.
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P2093
P2860
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P1476
Hyperplastic gastric tumors in ...... COX-2/mPGES-1 transgenic mice
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P2093
Hiroko Oshima
Kayo Inaba
Makoto M Taketo
Masanobu Oshima
P2860
P304
P356
10.1038/SJ.EMBOJ.7600170
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P577
2004-03-11T00:00:00Z