Engineering ligand-responsive gene-control elements: lessons learned from natural riboswitches.
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Reengineering orthogonally selective riboswitchesInsights into the Regulatory Landscape of the Lysine RiboswitchRiboswitches: structures and mechanismsAllosteric DNA nanoswitches for controlled release of a molecular cargo triggered by biological inputs.Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation.Artificial riboswitches for gene expression and replication control of DNA and RNA viruses.Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells.New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymesGene regulation by riboswitches with and without negative feedback loop.Reprogramming cellular behavior with RNA controllers responsive to endogenous proteinsChemistry of nucleic acids: impacts in multiple fields.Basis for ligand discrimination between ON and OFF state riboswitch conformations: the case of the SAM-I riboswitch.Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses.Multiscale methods for computational RNA enzymology.Role of ion valence in the submillisecond collapse and folding of a small RNA domain.Ribozyme Catalysis with a Twist: Active State of the Twister Ribozyme in Solution Predicted from Molecular Simulation.Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering.Emerging applications of riboswitches in chemical biology.Biomolecular engineering of intracellular switches in eukaryotesEmerging biomedical applications of synthetic biology.The many faces of the hairpin ribozyme: structural and functional variants of a small catalytic RNA.The dual aptamer approach: rational design of a high-affinity FAD aptamer.Dual transcriptional-translational cascade permits cellular level tuneable expression control.Translational repression using BIV Tat peptide-TAR RNA interaction in mammalian cells.Synthetic Botany.Twister ribozymes as highly versatile expression platforms for artificial riboswitches.Cell biology. The case for RNA.An adaptor from translational to transcriptional control enables predictable assembly of complex regulation.Formation of a ligand-assisted complex of two RNA hairpin loops.Ligand-dependent upregulation of ribosomal shunting.Systematic optimization of L-tryptophan riboswitches for efficient monitoring of the metabolite in Escherichia coli.A Capture-SELEX Strategy for Multiplexed Selection of RNA Aptamers Against Small Molecules.Optimization of Membrane Protein Production Using Titratable Strains of E. coli.Bacterial Riboswitch Discovery and AnalysisSmall synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting
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Engineering ligand-responsive gene-control elements: lessons learned from natural riboswitches.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Engineering ligand-responsive ...... ned from natural riboswitches.
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Engineering ligand-responsive ...... ned from natural riboswitches.
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type
label
Engineering ligand-responsive ...... ned from natural riboswitches.
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Engineering ligand-responsive ...... ned from natural riboswitches.
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Engineering ligand-responsive ...... ned from natural riboswitches.
@en
Engineering ligand-responsive ...... ned from natural riboswitches.
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Engineering ligand-responsive ...... ned from natural riboswitches.
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10.1038/GT.2009.81
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2009-07-09T00:00:00Z