The connection domain mutation N348I in HIV-1 reverse transcriptase enhances resistance to etravirine and rilpivirine but restricts the emergence of the E138K resistance mutation by diminishing viral replication capacity.

The connection domain mutation N348I in HIV-1 reverse transcriptase enhances resistance to etravirine and rilpivirine but restricts the emergence of the E138K resistance mutation by diminishing viral replication capacity.

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http://www.wikidata.org/entity/Q37547275
Current perspectives on HIV-1 antiretroviral drug resistanceEffects of the W153L substitution in HIV reverse transcriptase on viral replication and drug resistance to multiple categories of reverse transcriptase inhibitors.Impact of drug resistance-associated amino acid changes in HIV-1 subtype C on susceptibility to newer nonnucleoside reverse transcriptase inhibitors.Frequent Cross-Resistance to Dapivirine in HIV-1 Subtype C-Infected Individuals after First-Line Antiretroviral Therapy Failure in South AfricaIdentification of Novel Resistance-Related Polymorphisms in HIV-1 Subtype C RT Connection and RNase H Domains from Patients Under Virological Failure in Brazil.Effects of HIV-1 reverse transcriptase connection subdomain mutations on polypurine tract removal and initiation of (+)-strand DNA synthesis.Compensatory role of double mutation N348I/M184V on nevirapine binding landscape: insight from molecular dynamics simulation.Role of phenotypic investigation in the era of routine genotypic HIV-1 drug resistance testing
P2860

The connection domain mutation N348I in HIV-1 reverse transcriptase enhances resistance to etravirine and rilpivirine but restricts the emergence of the E138K resistance mutation by diminishing viral replication capacity.

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http://www.wikidata.org/entity/Q37547275
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The connection domain mutation ...... ng viral replication capacity.
@en
The connection domain mutation ...... ng viral replication capacity.
@nl
type
label
The connection domain mutation ...... ng viral replication capacity.
@en
The connection domain mutation ...... ng viral replication capacity.
@nl
prefLabel
The connection domain mutation ...... ng viral replication capacity.
@en
The connection domain mutation ...... ng viral replication capacity.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
The connection domain mutation ...... ng viral replication capacity.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932